Chronic Kidney Disease and Pharmacoepidemiology in Older Individuals: Challenges, Insights, and Therapeutic Advances
A special issue of Geriatrics (ISSN 2308-3417).
Deadline for manuscript submissions: 15 September 2025 | Viewed by 844
Special Issue Editor
Interests: pharmacoepidemiology; biostatistics; geriatric syndromes; multimorbidity; frailty; chronic kidney disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chronic kidney disease (CKD) is a growing concern in older populations, where the interplay of aging-related physiological changes, multimorbidity, and medication complexities presents unique challenges. CKD in older adults often goes undiagnosed or undertreated due to atypical presentations and limitations in conventional diagnostic approaches. Furthermore, the coexistence of multiple chronic conditions in this demographic leads to polypharmacy, increasing the risk of drug–drug interactions, adverse drug events, and medication nonadherence. The decline in renal function also significantly impacts pharmacokinetics and pharmacodynamics, necessitating careful adjustment of dosages and drug regimens to ensure safety and efficacy. This Special Issue seeks to delve into the intersection of CKD and pharmacoepidemiology in older individuals, emphasizing the challenges, therapeutic advancements, and insights gained from real-world data. Contributions will address areas such as the optimization of pharmacotherapy, the development of personalized medicine strategies, and the integration of innovative therapies tailored for this vulnerable group. By bringing together original research, systematic reviews, and expert perspectives, this issue aims to provide a comprehensive resource for clinicians, researchers, and policymakers to enhance care and improve outcomes for older adults living with CKD.
Dr. Luca Soraci
Guest Editor
Manuscript Submission Information
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Keywords
- chronic kidney disease (CKD)
- pharmacoepidemiology
- older adults
- polypharmacy
- multimorbidity
- therapeutic advances
- potentially inappropriate medications
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