Bacterial DNA Organization and Segregation

Dear colleagues,

Bacterial genomes are highly dynamic and diverse. They are composed of a primary chromosome and a variable number of other replicons, including secondary chromosomes and plasmids. All these replicons are folded to compact DNA. At the same time, they manage all the processes involved in DNA metabolism. How these different DNA molecules are organized in a unique cellular compartment to faithfully segregate these varieties of replicons is still under intense investigation. Numerous controlled mechanisms are at play and are interconnected to achieve their transmission and maintenance over generations.

This Special Issue of Genes on “Bacterial DNA Organization and Segregation” will address the mechanisms by which bacteria organize their genomes and manage the segregation and maintenance of all the replicons, providing an overview of recent developments in specialized research topics and of critical perspectives on upcoming challenges. We welcome original research articles and reviews.

We look forward to receiving your contributions.

Dr. Jean-Yves Bouet 
Guest Editor

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