MicroRNAs and Mitochondrial Dynamics in Heart Regeneration

Dear Colleagues,

In recent decades, research has shown key roles for MicroRNAs (miRNAs) in the post-transcriptional regulation of gene expression in major cardiac physiological and pathological events. Indeed, there has been an exponential growth in studies reporting the contribution of microRNAs to various processes underlying the pathology of cardiac muscle and as well as to potential therapeutic targets.

On the other hand, cardiomyocyte mitochondria are known to be highly dynamic, continuously moving and undergoing fission and fusion, forming interconnected networks; however, the involvement of these processes in heart disease and health is not fully understood. Abnormal mitochondrial dynamics lead to dysfunctional mitochondria and thus disrupt energy production and increase oxidative stress, resulting in cardiomyocyte apoptosis and heart tissue damage.

In this Special Issue entitled “MicroRNAs and Mitochondrial Dynamics in Heart Regeneration”, we would like to present the current progress in the heart field regarding these two important topics. We welcome original research papers and updated reviews on new insights into the pathogenesis, regulatory pathways and beneficial roles of miRNAs and mitochondrial dynamics in heart regeneration.

Dr. Eltyeb Abdelwahid
Dr. Katherine Athayde Teixeira de Carvalho
Guest Editors

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