Molecular Mechanisms in Transplant-Related Diseases: After Solid Organ/Bone Marrow Transplantation
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: closed (20 January 2024) | Viewed by 309
Special Issue Editor
Interests: genetics in liver and cardiovascular diseases; molecular mechanisms in transplant-related diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Solid organ/bone marrow transplantation is considered the optimal therapeutic choice for end-stage organ and hematological diseases. It can significantly increase patient survival and improve quality of life. However, transplantation is not a panacea. Despite significant surgical and immune pharmacological advancements, transplant recipients still do not acquire the life expectancy of their age-matched healthy peers. For example, because of the lifetime use of immunosuppressive drugs, the risk of infection is significantly increased in transplant recipients. Moreover, acute and chronic rejection, graft-versus-host disease, cardiovascular diseases, medication-related adverse effects, metabolic diseases (including diabetes mellitus, hyperlipidemia, hypertension, osteopenia/osteoporosis, etc.), and many other transplant-related diseases have a strong impact on the allograft and patient survival. The molecular mechanisms in transplant-related diseases remain unclear, and understanding of the molecular mechanisms of this area is still a major challenge at present. Therefore, this Special Issue provides us with an opportunity to deeply discuss the molecular mechanisms in transplant-related diseases. In this Special Issue, we welcome submissions of original research (basic and clinical research), case reports, and review articles focusing on, but not limited to, molecular mechanisms in transplant-related diseases after solid organ and bone marrow transplantation.
Dr. Yuanyuan Zhao
Guest Editor
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Keywords
- solid organ transplantation
- bone marrow transplantation
- transplant-related diseases
- molecular mechanisms
- genetics
- risk factors
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