Molecular Genetics and Pathogenesis of Motor Neuron Disease
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Neurogenomics".
Deadline for manuscript submissions: 25 November 2025 | Viewed by 885
Special Issue Editor
2. Division of Cell Proliferation, Tohoku University Graduate School of Medicine, Sendai 980-8576, Japan
Interests: motor neuron disease; neurodevelopmental disorders; ubiquitin; chromatin
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Motor neuron disease is a debilitating disorder for which effective therapeutics have been elusive for centuries. Research advancements, particularly those supported by evolving technologies, such as DNA, RNA, and protein omics, have gradually culminated clinically effective treatments, as exemplified by Onasemnogene abeparvovec, which targets spinal muscular atrophy. While further advances are anticipated, satisfactory therapies remain unavailable. To promote research that is crucial for therapeutic development in motor neuron disease, this Special Issue will consist of a collection of original research and comprehensive review articles focusing on molecular genetics and analyses of motor neuron disease at the molecular, cellular, and phenotypic levels. These articles will aim not only to reaffirm the recent research progress for scholars already engaged in motor neuron disease but also to ignite interest among researchers not yet involved in this field, providing fresh insights into this disorder.
Dr. Tadashi Nakagawa
Guest Editor
Manuscript Submission Information
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Keywords
- motor neuron disease
- molecular genetics
- molecular and cellular analyses
- phenotypic characterization
- therapeutic development
- clinical applications
- omic technologies
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