The Spatial Organisation of Chromosomes and Genes
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 15 May 2026 | Viewed by 438
Special Issue Editors
Interests: chromosome biology and disease
Special Issue Information
Dear Colleagues,
We are pleased to invite submissions to the upcoming Special Issue of Genes, “The Spatial Organisation of Chromosomes and Genes.” This Special Issue aims to showcase recent advances in understanding how the 3D genome controls cellular function through spatial organization and dynamic chromatin folding. We welcome studies focusing on method development—including genomic, computational, and imaging approaches—to map chromatin architecture at high resolution; mechanistic studies that dissect how molecular regulators such as cohesin and CTCF mediate loop extrusion, TAD and compartment formation; and functional studies exploring how 3D genome organization modulates gene regulation, enhancer–promoter interactions, and cellular identity. We particularly encourage integrative and interdisciplinary approaches that bridge structure and function to reveal new principles of genome organization.
Dr. Yu Liu
Dr. Lingluo Chu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- 3D genome
- cohesin
- CTCF
- TAD
- compartment
- loop extrusion
- gene regulation
- enhancer–promoter interactions
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
