Genetic Improvement and Genome Editing Strategies in Silkworm (Bombyx mori) Breeding

Dear Colleagues,

The silkworm (Bombyx mori) is not only an economically important insect for silk production but also a well-established lepidopteran model for genetic research, functional genomics, and applied breeding. With the rapid development of genome sequencing, functional genomics, and genome editing technologies, silkworm research has entered a new stage characterized by precise genetic manipulation and trait-oriented improvement. This Special Issue aims to collect recent advances demonstrating how modern genetic and genomic approaches can be applied to silkworm trait improvement and breeding innovation. We welcome studies employing genome editing technologies, such as CRISPR/Cas9 systems, transgenic strategies, and gene regulatory manipulation, to improve economically important traits, including silk yield and quality, stress and disease resistance, metabolic traits, and developmental performance. Contributions focusing on gene discovery, functional validation, regulatory network analysis, and multi-omics integration—such as genomics, transcriptomics, proteomics, and epigenomics—are particularly encouraged. In addition to original research articles, this Special Issue also welcomes review papers that summarize emerging technologies, breeding strategies, and future perspectives in silkworm genetic improvement. By integrating fundamental genetic mechanisms with applied breeding strategies, this Special Issue aims to provide a comprehensive platform for advancing silkworm breeding research and promoting sustainable innovation in sericulture.

Dr. Qingsong Liu
Guest Editor

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