Advances in Molecular Genetics of Psychiatric Diseases

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: 20 January 2026 | Viewed by 13

Special Issue Editor


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Guest Editor
Department of Food Science and Nutrition, University of the Aegean, Myrina, Lemnos, Greece
Interests: genomics; genetics; psychiatric genetics; immunogenetics; GWAS; structural variation; rare variant analysis; single-cell RNA sequencing

Special Issue Information

Dear Colleagues,

Recent advances in molecular genetics have begun to unravel the complex biological underpinnings of psychiatric disorders, offering new insights into their etiology, diagnosis, and potential treatment strategies. The integration of genome-wide association studies (GWAS), whole-genome and exome sequencing, transcriptomics, and epigenomic profiling has identified numerous risk loci, rare variants, and regulatory mechanisms involved in disorders such as schizophrenia, bipolar disorder, major depressive disorder, autism spectrum disorder, and anxiety-related conditions. These findings not only enhance our understanding of gene–environment interactions and brain development but also pave the way for precision psychiatry.

In this Special Issue, we welcome original research and review articles that explore the molecular and genetic basis of psychiatric diseases. Topics may include, but are not limited to, genetic architecture, functional genomics, transcriptomic signatures, rare variant analyses, epigenetic regulation, gene–environment interactions, and novel bioinformatic- or model-based approaches in psychiatric genetics.

Dr. Fotis Tsetsos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • psychiatric genetics
  • molecular psychiatry
  • GWAS
  • rare variants
  • transcriptomics
  • epigenetics
  • gene-environment interactions
  • precision psychiatry
  • schizophrenia
  • bipolar disorder
  • depression
  • autism spectrum disorder
  • anxiety
  • functional genomics
  • neurodevelopmental disorders

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Published Papers

This special issue is now open for submission.
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