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Gastrointestinal Disorders
Special Issues
Recent Advances in Pediatric Gastroenterology, Hepatology, and Nutrition
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Recent Advances in Pediatric Gastroenterology, Hepatology, and Nutrition

A special issue of Gastrointestinal Disorders (ISSN 2624-5647).

Deadline for manuscript submissions: 25 November 2025 | Viewed by 2831

Special Issue Editors

Dr. Rajmohan Dharmaraj

E-Mail Website
Guest Editor
Division of Gastroenterology, Department of Pediatrics, University of New Mexico, Albuquerque, NM 87131, USA
Interests: inflammatory bowel disease; pediatric nutrition; endoscopic procedures
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Andrew Day

E-Mail Website
Guest Editor
Department of Paediatrics, Christchurch Hospital, University of Otago, Christchurch 4710, New Zealand
Interests: inflammatory bowel disease; coeliac disease; improving Crohn’s outcomes; intestinal inflammatory biomarkers; nutritional aspects of gut diseases; host–pathogen interactions in the gut (and how these relate to chronic gut diseases)
Special Issues, Collections and Topics in MDPI journals
Dr. Rasha A Elmaoued

E-Mail Website
Guest Editor
Division of Gastroenterology, Department of Pediatrics, University of New Mexico, Albuquerque, NM 87131, USA
Interests: pediatric gastroenterology

Special Issue Information

Dear Colleagues,

The field of pediatric gastroenterology, hepatology, and nutrition is rapidly evolving due to scientific advances and the increasing prevalence of relevant disorders. Our knowledge in several key areas has expanded significantly over the last decade. This includes greater insight into the etiology and management of conditions such as inflammatory bowel disease, eosinophilic esophagitis, and liver diseases. We have also made progress in understanding the role of the intestinal microbiome in health and disease, as well as improving diagnostic testing and imaging studies in children. New treatments, such as personalized medicine approaches using genetic testing for inflammatory bowel disease, are being adopted for complex conditions. However, there are still many gaps in our knowledge of many gastrointestinal conditions in children.

This Special Issue aims to collect and publish original research articles and reviews demonstrating recent advances in the etiology, diagnosis, and treatment of conditions across the field of pediatric gastroenterology, hepatology, and nutrition. Authors are also invited to explore various aspects such as pathophysiology, prevention, supportive care, long-term outcomes, epidemiology, organization of care, and the economic impact of these diseases.

We look forward to receiving your contributions.

Dr. Rajmohan Dharmaraj
Prof. Dr. Andrew Day
Dr. Rasha A Elmaoued
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gastrointestinal Disorders is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inflammatory bowel disease
  • celiac disease
  • food allergies
  • functional gastrointestinal disorders
  • nutritional disorders
  • pediatric liver diseases

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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14 pages, 257 KB  
Article
Attitudes Among Pediatric Gastroenterologists Toward Vaccination Based on an Anonymous Online Survey
by Elizaveta Makarova, Tatyana Gabrusskaya, Ekaterina Kharitonova, Natalia Ulanova, Natalia Volkova, Maria Revnova, Dmitri Ivanov and Mikhail Kostik
Gastrointest. Disord. 2025, 7(3), 54; https://doi.org/10.3390/gidisord7030054 - 23 Aug 2025
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Abstract
Background: Children with inflammatory bowel disease (IBD) are at heightened risk for vaccine-preventable infections because of underlying immune dysregulation and long-term immunosuppressive therapy. Despite published guidelines affirming vaccine safety, real-world coverage remains suboptimal. It is a pilot, single-country survey designed to explore [...] Read more.
Background: Children with inflammatory bowel disease (IBD) are at heightened risk for vaccine-preventable infections because of underlying immune dysregulation and long-term immunosuppressive therapy. Despite published guidelines affirming vaccine safety, real-world coverage remains suboptimal. It is a pilot, single-country survey designed to explore baseline knowledge and practices regarding vaccination in paediatric IBD within a specific local healthcare context. Objective: The objective of this study is to evaluate the knowledge, attitudes, and practices of paediatric gastroenterologists (PGs) regarding the immunisation of children with IBD. Methods: We conducted an exploratory pilot, cross-sectional survey of paediatric gastroenterologists in Russia, focusing on immunisation knowledge and practical barriers in routine care. A cross-sectional, anonymous online survey was distributed to PGs nationwide between January 2022 and April 2022. The online questionnaire explored demographic characteristics, awareness of international recommendations, perceptions of vaccine safety at various disease and treatment stages, and routine vaccination practices. Responses were analysed with non-parametric statistics (α = 0.05). In a parallel prospective cohort, the vaccination certificates of 98 paediatric IBD patients (January 2022–April 2023) were audited to quantify real-world coverage. Results: Fifty-one PGs completed the survey. Forty-one per cent agreed that vaccines do not provoke IBD flares, while 17.6% considered live vaccines acceptable during immunosuppressive remission. Nearly one-third (32%) did not personally oversee immunisation, and 18% occasionally discouraged vaccination during therapy. Only 35.3% deemed baseline serology essential before starting immunosuppression; 46.5% supported antibody checks immediately prior to vaccination. The certificate audit revealed a full schedule completion rate of 66.3% for measles–mumps–rubella and 74.2% for hepatitis B, contrasting with parental reports of 82.3% complete coverage. Conclusions: Knowledge gaps, limited guideline awareness, and parental concerns contribute to suboptimal vaccination of paediatric IBD patients. Targeted educational initiatives, clearer shared-care pathways, and routine certificate audits are needed to close the coverage gap and reduce infection-related morbidity. Findings are hypothesis-generating and reflect local practice; as a pilot study, results should be interpreted with caution and may not generalise beyond similar settings. Full article
(This article belongs to the Special Issue Recent Advances in Pediatric Gastroenterology, Hepatology, and Nutrition)

Review

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18 pages, 876 KB  
Review
Metabolic Bone Disease in Pediatric Patients with Short Bowel Syndrome
by Hannah DeGonza, Sarah Laurenzano, Janna Galinato, Rasha Elmaoued, Razan Alkhouri, Ricardo Orlando Castillo and Rajmohan Dharmaraj
Gastrointest. Disord. 2025, 7(1), 16; https://doi.org/10.3390/gidisord7010016 - 16 Feb 2025
Viewed by 1830
Abstract
Metabolic bone disease (MBD) is a known complication of short bowel syndrome (SBS), with a high prevalence in both pediatric and adult populations. MBD includes various conditions that disrupt skeletal homeostasis, such as rickets, osteomalacia, and osteoporosis. The pathogenesis of MBD is multifactorial, [...] Read more.
Metabolic bone disease (MBD) is a known complication of short bowel syndrome (SBS), with a high prevalence in both pediatric and adult populations. MBD includes various conditions that disrupt skeletal homeostasis, such as rickets, osteomalacia, and osteoporosis. The pathogenesis of MBD is multifactorial, regardless of the underlying cause of SBS. When MBD is suspected, it is important to conduct laboratory evaluations to guide proper diagnosis and treatment. Dual-energy X-ray absorptiometry (DXA) is the preferred imaging modality for assessing MBD in routine clinical care. Early and accurate diagnosis and treatment of MBD in pediatric patients with SBS are essential to support growth and development and prevent fractures and metabolic complications. Using the best evidence available, this article aims to review the pathophysiology, diagnosis, and current management of MBD in pediatric patients with SBS. Full article
(This article belongs to the Special Issue Recent Advances in Pediatric Gastroenterology, Hepatology, and Nutrition)
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