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The main topics for the ICCBM-16 are: Theory and practice of crystallization; Sample preparation and handling in advanced techniques; Crystals for "high resolution studies"; Membrane proteins; Structure diversity of bio-macromolecules; Crystallization of conformationaly unstable proteins and other crystallization resisting (challenging) bio-macromolecules; Automation techniques in crystallization;Crystallization in industry and drug design; Crystallography in education etc.