Generative AI in Action: Trends, Applications, and Implications

A special issue of Computation (ISSN 2079-3197).

Deadline for manuscript submissions: 15 June 2025 | Viewed by 1157

Special Issue Editors


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Guest Editor
Lincoln Institute of Higher Education, Sydney, NSW 2000, Australia
Interests: agent-based modeling

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Guest Editor
School of Engineering and Technology, Central Queensland University, Sydney, NSW 2000, Australia
Interests: artificial intelligence; machine learning; security; QoS; Internet of Things; computer networks security; cybersecurity; blockchain; computer networks; computer security
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Special Issue Information

Dear Colleagues,

As generative AI (GenAI) rapidly advances, it continues to unlock unprecedented opportunities for innovation across numerous fields. This Special Issue on "Generative AI in Action: Trends, Applications, and Implications" seeks to explore the most promising developments and applications of GenAI. GenAI’s potential to generate complex data, automate content creation, and enhance machine learning workflows is transforming industries such as healthcare, finance, legal services, and entertainment. The significance of this research area cannot be overstated, as it bridges traditional machine learning techniques with emerging models that enable novel capabilities and experiences.

We are pleased to invite you to submit your research to this Special Issue, which aligns closely with the journal’s mission of advancing the interdisciplinary applications of AI and expanding the understanding of its practical impacts. This Special Issue aims to capture GenAI’s role in reshaping workflows, improving user experience, and addressing both technological and operational challenges in a way that directly contributes to the journal’s focus. In this Special Issue, we welcome original research articles and review papers that address GenAI’s applications and implications across various fields.

We look forward to receiving your contributions and to collaborating towards advancing the understanding of GenAI’s applications and impacts. This Special Issue aims to offer a platform for high-quality impactful research that addresses current challenges and future opportunities within this dynamic area.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Emerging trends in generative AI.
  • Applications of GenAI in industry-specific contexts (all industries are welcome).
  • Use of GenAI in machine learning workflows.
  • Challenges in the applications and uses of GenAI.
  • Security issues in GenAI application.
  • Ethical and responsible use of GenAI.
  • Future directions and emerging opportunities.

Dr. Xin Gu
Dr. Fariza Sabrina
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Computation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • generative AI
  • machine learning
  • natural language processing
  • large language models
  • data engineering

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Published Papers (1 paper)

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Research

24 pages, 7611 KiB  
Article
Advancements in Predictive Analytics: Machine Learning Approaches to Estimating Length of Stay and Mortality in Sepsis
by Houssem Ben Khalfallah, Mariem Jelassi, Jacques Demongeot and Narjès Bellamine Ben Saoud
Computation 2025, 13(1), 8; https://doi.org/10.3390/computation13010008 - 1 Jan 2025
Viewed by 739
Abstract
Sepsis remains a major global health concern, causing high mortality rates, prolonged hospital stays, and substantial economic burdens. The accurate prediction of clinical outcomes, such as mortality and length of stay (LOS), is critical for optimizing hospital resource allocation and improving patient management. [...] Read more.
Sepsis remains a major global health concern, causing high mortality rates, prolonged hospital stays, and substantial economic burdens. The accurate prediction of clinical outcomes, such as mortality and length of stay (LOS), is critical for optimizing hospital resource allocation and improving patient management. The present study investigates the potential of machine learning (ML) models to predict these outcomes using a dataset of 1492 sepsis patients with clinical, physiological, and demographic features. After rigorous preprocessing to address missing data and ensure consistency, multiple classifiers, including Random Forest, Extra Trees, and Gradient Boosting, were trained and validated. The results demonstrate that Random Forest and Extra Trees achieve high accuracy for LOS prediction, while Gradient Boosting and Bernoulli Naïve Bayes effectively predict mortality. Feature importance analysis identified ICU stay duration (ICU_DAYS_OBS) as the most influential predictor for both outcomes, alongside vital signs, white blood cell counts, and lactic acid levels. These findings highlight the potential of ML-driven clinical decision support systems (CDSSs) to enhance early risk assessment, optimize ICU resource planning, and support timely interventions. Future research should refine predictive features, integrate advanced biomarkers, and validate models across larger and more diverse datasets to improve scalability and clinical impact. Full article
(This article belongs to the Special Issue Generative AI in Action: Trends, Applications, and Implications)
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