Special Issue "Catalysts for Structure-Functional Analysis and Enzyme Optimization"
Deadline for manuscript submissions: 15 April 2021.
Interests: screening for enzymatic activities; enzymology; enzyme engineering; transglycosylation; enzymatic synthesis of carbohydrates; glycoside–hydrolases
Interests: protein folding, functional amyloids, conformational transitions, peptide inhibitors, antiviral drugs, supramolecular complexes
The knowledge of an enzyme’s catalytic mechanism can be of fundamental importance and a critical factor in the design and synthesis of compounds having biotechnological or therapeutic potential. The research is therefore multidisciplinary by its very nature and includes mechanistic enzymology, recombinant DNA (site-directed mutagenesis), as well as organic synthesis, medicinal/bioorganic chemistry, supramolecular chemistry, molecular modeling, and structural biology. Using the tools of chemo-organic synthesis, biochemistry, and computer modeling, this work aims to provide increased understanding of the chemical principles underlying mechanisms of action of natural catalysts with targeted activity. Structural models of the substrate enzyme complex are useful in order to investigate in detail the roles of the enzyme amino acid residues in its activity and the scope and limitation of substrates.
We invite researchers to contribute into this Special Issue in order to share their up-to-date knowledge on structure–functional aspects of enzyme functionality and achievements in engineering enzymes with new catalytic activity.
Dr. Anna A. Kulminskaya
Dr. Vladimir V. Egorov
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Protein engineering
- Synthetic biology
- Industrial enzymes
- Bio-based chemicals
- Enzyme structure
- Protein folding
- Peptide design
- Supramolecular chemistry