Synthetic Enzyme Cascades
A special issue of Catalysts (ISSN 2073-4344). This special issue belongs to the section "Biocatalysis".
Deadline for manuscript submissions: 20 July 2026 | Viewed by 2
Special Issue Editor
Interests: biocatalysis; enzyme engineering; directed evolution; enzymology; multi-enzymatic cascades; biosynthesis
Special Issue Information
Dear Colleagues,
The unparalleled characteristics of high selectivity, excellent sustainability, and operation under mild conditions have established biocatalysis as an ideal technology for the synthesis of diverse products, including pharmaceutically relevant chemicals, fine chemicals, and food additives. Constructing multi-enzymatic cascades by leveraging the compatibility and synergy of different enzymes in a tandem reaction system enables promising and even unprecedented routes to value-added products. These biocatalytic routes could serve as greener, safer, more straightforward, and more cost-effective alternatives to traditional chemical transformations. Today, the rapid expansion of the biocatalytic toolbox—through the discovery of new enzyme reactivities and the engineering of existing enzymes for improved performance—offers new opportunities for developing versatile synthetic enzyme cascades. In this context, we invite you to submit original research articles and/or reviews that present important findings on the design, construction, and synthetic applications of multi-enzymatic cascades, which will be illuminating contributions for the biocatalysis and organic chemistry communities.
Dr. Fei-Fei Chen
Guest Editor
Manuscript Submission Information
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Keywords
- biocatalysis
- multi-enzymatic cascades
- multistep tandem reactions
- one-pot reaction
- enzyme engineering
- green chemistry
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