Frontiers of Electronic Biochip and Biosensors

Dear Colleagues,

The worth of a biochip or biosensor can be determined based on three basic requirements, namely, specificity, sensitivity, and user-friendliness. Specificity is usually achieved through the bioprobe with a unique biomolecular recognition. Determining how to reliably and sensitively obtain signals from bioprobe–target molecular interactions and improve the user-friendliness of the entire detection system is critical. Integration/fusion of modern electronics into biosensing has the potential to revolutionize current diagnostics practice. In molecular biology, biochips are generally regarded as a microarray that contains miniaturized test sites arranged on a solid substrate for high throughput detection. Following the integration of electronic elements, such as by changing the microarray chip from glass to a semiconductor IC chip, the function of a biochip may be similar to that of a biosensor that normally contains a transducer for direct sensing, and the biochip can thus be developed into a standalone device for point-of-care applications. Advances in modern electronics industries have provided novel opportunities for these developments and can effectively help toward participation in global trends in digital healthcare systems. Electronic biochips and biosensors may include any electronic devices used for biomolecular detection. 

Prof. Dr. Yuh-Shyong Yang
Dr. Chi-Chang Wu
Guest Editors

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