Special Issue "Gene Therapy Strategies for HIV/AIDS"
A special issue of Biomedicines (ISSN 2227-9059).
Deadline for manuscript submissions: closed (30 January 2016).
Interests: hematopoietic stem cell gene therapy; foamy retroviral vectors; vector-mediated genotoxicity; retroviral mutagenesis screens for cancer drivers
This Special Issue “Gene Therapy Strategies for HIV/AIDS” will focus on novel approaches to treat HIV/AIDS using gene transfer.
The cure of the “Berlin patient” by transplantation of allogeneic hematopoietic stem cells has provided a proof of principle that HIV/AIDS can be treated using genetically resistant stem cells. This has led to preclinical and clinical studies exploring numerous approaches to create genetically modified hematopoietic stem cells and T cells that resist HIV infection. In addition, means to deliver transgenes encoding broadly neutralizing antibodies or antibody-fusions to muscle cells have shown great promise.
This issue will focus on novel approaches to HIV gene therapy, vector efficacy and safety, preclinical models and immunogenicity, and translation to the clinic.
Dr. Grant Trobridge
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- HIV gene therapy
- viral vector
- stem cell gene therapy
- gene targeting
- preclinical models