Functional Products Used in Alleviation of Oxidative Stress Diseases and Interaction with Human Microbiota

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Gene and Cell Therapy".

Deadline for manuscript submissions: closed (1 March 2020) | Viewed by 6190

Special Issue Editors

Department of Genetics, Faculty of Biology, University of Bucharest, 050663 Bucharest, Romania
Interests: cell biology; microbial molecular biology; microbiota; virulence factors; antimicrobials
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Special Issue Information

Dear Colleagues,

Functional products (like probiotics, prebiotics, dietary fibers, plant extracts, etc.) are useful tools in the reduction or alleviation of the  pathological effects of oxidative stress. The development of innovative  products is a significant research area with producing evidence of disease  control and prevention. Thus, we will collect new studies that could present in vitro/in vivo evidence of a modulation response through the  microbiota pattern. You are also invited to contribute research based on  the effect of different drugs that are used in degenerative pathologies and  possible interactions with the human microbiota. Side effects are significant in disease management and interactions with associated pathologies. We would like to encourage you to send papers on these and other related  aspects relevant to the issue.

Assoc. Prof. Dr. Emanuel Vamanu
Assoc. Prof. Dr. Diana Roxana Pelinescu
Guest Editors

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Keywords

  • product administration
  • functional quality
  • microbiota modulation
  • pathology – microbiota
  • immunomodulatory effects
  • polyphenols
  • pro-, pre-, synbiotic, nutraceuticals
  • drugs
  • free radicals
  • antioxidant

Published Papers (1 paper)

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Review

14 pages, 2857 KiB  
Review
Correlations between Microbiota Bioactivity and Bioavailability of Functional Compounds: A Mini-Review
by Emanuel Vamanu and Florentina Gatea
Biomedicines 2020, 8(2), 39; https://doi.org/10.3390/biomedicines8020039 - 20 Feb 2020
Cited by 61 | Viewed by 5761
Abstract
Numerous studies have demonstrated the role of the microbiota in supporting the physiological functions, owing to its metabolomic component. The presence of biocomponents generally leads to the correction of the microbial pattern correlated with the reduction of oxidative pressure. This study aims to [...] Read more.
Numerous studies have demonstrated the role of the microbiota in supporting the physiological functions, owing to its metabolomic component. The presence of biocomponents generally leads to the correction of the microbial pattern correlated with the reduction of oxidative pressure. This study aims to present the main processes that correlate the bioavailability and bioactivity of some functional components through the action of the human microbiota. The use of probiotics and prebiotics is an innovative manner involving alternatives that increase the bioavailability of certain natural or metabolic components has been proposed. Probiotic strains (Saccharomyces cerevisiae or Lactobacillus (L.) plantarum) may represent an intermediary for increasing the antioxidant bioactivity, and they may be administered in the form of a biomass enriched with functional compounds, such as phenolic acids. The limiting effect of gastrointestinal transit is, in several cases, the key to the biopharmaceutical value of new products (or supplements). The identification of newer ways of formulating supplements also involves the compatibility of different types of products, the testing of bioaccessibility, and the elimination of biotransformations. Full article
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