Skin Diseases: From Molecular Mechanisms to Novel Therapeutic Approaches
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 89
Special Issue Editor
Special Issue Information
Dear Colleagues,
The skin, the largest organ of the human body, is associated with diseases that rank first in global prevalence and third in disease burden. Advances in basic, translational, and clinical research have deepened our understanding of pathogenesis, drug development, and therapeutic strategies in the context of skin diseases. Molecular dependencies identified in these processes have enabled clinicians to refine disease classification, diagnosis, and treatment approaches, thereby advancing personalized precision medicine. However, the pathogenesis of and therapeutic strategies for skin diseases warrant further exploration. This Special Issue invites the submission of original research and review articles that focus on molecular mechanisms and therapeutic strategies, with the aim of elucidating molecular factors (including but not limited to genetic, epigenetic, signaling, metabolic, and immune-related components) and the underlying dermatological pathogenesis and developing therapeutic interventions targeting these factors. Topics of particular interest include the following:
- Therapeutic potential of targeting cell death pathways in skin diseases;
- Molecular regulatory networks in skin barrier dysfunction;
- Interplay between the skin microbiome and immune microenvironment;
- Epigenetic reprogramming in chronic inflammatory skin diseases;
- Metabolic adaptations in the skin tumor microenvironment;
- Non-histaminergic mechanisms of pruritus signaling pathways;
- Drug resistance mechanisms and dynamic monitoring technologies;
- Stem cell exhaustion mechanisms in skin aging.
We look forward to receiving your contributions to this Special Issue.
Dr. Guangtong Deng
Guest Editor
Manuscript Submission Information
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Keywords
- skin diseases
- cell death
- ferroptosis
- cuproptosis
- melanoma
- cancer immunotherapy
- psoriasis
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