Innovative Biomaterials and Advanced Techniques for Bone Regeneration Applications
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Biomedical Engineering and Materials".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 122
Special Issue Editor
Interests: smart biomaterials for tissue engineering; ceramo-polymeric hybrid systems; hybrid smart structures; new theoretical approaches for biomimetic material and prostheses
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bone regeneration is crucial in various surgical fields, such as neurosurgery, orthopaedics, traumatology, and orofacial surgery. Repairing critical-size bone defects poses a significant clinical challenge in implant surgery, where highly biologically demanding scenarios, such as in osteogenesis and angiogenesis, solely rely on the basal bone without any bony envelope. Due to their basic structural functions, the evolutionary path of skeletal bones’ morphology and microstructure has been necessarily strongly driven by biomechanical and biochemical features, either at macro or micro scales. Physical factors, such as oxygen and nutrient concentration, as well as mechanical stimuli, mediating cellular communication, are altered when using traditional monolithic implants. A more “biomimetic design” accounting for biomechanical as well mechanobiological needs is therefore required.
The potentialities of new additive manufacturing technologies using metallic, ceramic, and polymeric materials could foster innovative solutions for porous bone scaffolds and implants that are able to restore the correct biomechanics and local biological environment of skeletal bone. Contributions accounting for new materials, bone biomechanics and mechanobiology, new 3D-printed solutions, and clinical cases outlining the criticalities of traditional implant osteointegration and functional recovery are welcomed to create a basis for new biomimetic approaches to implantology.
Prof. Dr. Antonio Apicella
Guest Editor
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Keywords
- biomaterials
- bone regeneration
- osteointegration
- 3D printing
- biomimetic design
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