Musculoskeletal Disease: From Infectious to Neoplastic

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 3789

Special Issue Editor


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Guest Editor
Department of Radiology, Fondazione Policlinico Campus Bio-Medico University, 00128 Rome, Italy
Interests: oncologic imaging; female pelvic imaging; endometriosis; breast imaging; magnetic resonance imaging; computed tomography; contrast-enhanced mammography

Special Issue Information

Dear Colleagues,

Musculoskeletal disorders include a variety of conditions ranging from infective diseases to neoplastic lesions, and also involving joint and tendon structures, with different clinical and imaging features according to patient’s age, clinical onset, and the site of the disease. Imaging plays a pivotal role in characterizing these conditions and identifying the location and extent of disease involvement, in order to guide the correct clinical management and monitoring treatment response. Depending on the site of the disease, X-rays or ultrasound usually are the first imaging techniques performed; in particular, ultrasound is often preferred because of its low cost, large availability, portability, and potential for the real-time guidance of mass characterization. The widespread use of magnetic resonance (MR) and computed tomography (CT) has increased the diagnostic accuracy in conditions that require a multiplanar imaging approach or when US is limited. Moreover, CT and MRI allow a detailed evaluation of the extent of the disease, including the assessment of joint spaces, tendons, and osseous changes. The aim of this Special Issue is to provide a detailed description of the multiple disorders affecting the musculoskeletal system, with a special focus on imaging and its newest applications.

Dr. Claudia Lucia Piccolo
Guest Editor

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Keywords

  • magnetic resonance imaging
  • computed tomography
  • ultrasound
  • X-ray
  • artificial intelligence
  • neoplastic disorders
  • infectious diseases
  • acute trauma

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Published Papers (1 paper)

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Review

15 pages, 2131 KiB  
Review
Spondylodiscitis and Its Mimickers: A Pictorial Review
by Claudia Lucia Piccolo, Alberta Villanacci, Federica Di Stefano, Nicoletta Fusco, Davide Roberto Donno, Massimo Cristofaro, Fabrizio Taglietti and Stefania Ianniello
Biomedicines 2024, 12(11), 2566; https://doi.org/10.3390/biomedicines12112566 - 9 Nov 2024
Cited by 4 | Viewed by 3445
Abstract
Spondylodiscitis is an infection of the intervertebral disc, the adjacent vertebral body, and/or contiguous structures due to the introduction of infectious agent, usually by the hematogenous route. Imaging is crucial in assessing bacterial and tubercular spondylodiscitis, as well as their associated complications. Magnetic [...] Read more.
Spondylodiscitis is an infection of the intervertebral disc, the adjacent vertebral body, and/or contiguous structures due to the introduction of infectious agent, usually by the hematogenous route. Imaging is crucial in assessing bacterial and tubercular spondylodiscitis, as well as their associated complications. Magnetic resonance imaging in particular can clearly depict osteo-structural changes in the vertebral body and the associated disc, as well as any soft-tissue complications, such as paravertebral abscess and/or epidural abscess, improving disease characterization and helping to recognize the agent involved. Nevertheless, other non-infectious diseases may mimic imaging appearances of spondylodiscitis and one should be aware of these conditions when interpreting MR images, which include Modic type I degenerative changes, ankylosing spondylitis, acute Schmorl’s node, porotic fractures, and spinal neuropathy arthropathy. This pictorial review aims at describing imaging findings of bacterial and non-bacterial spondylodiscitis, complications, and those pathologies that mimic these infections. Full article
(This article belongs to the Special Issue Musculoskeletal Disease: From Infectious to Neoplastic)
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