Myelodysplastic Syndromes: Advances and Challenges in Pathophysiology and Therapeutic Approaches
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 238
Special Issue Editor
Special Issue Information
Dear Colleagues,
Myelodysplastic syndromes (MDS) are a group of heterogeneous myeloid clonal diseases originating from hematopoietic stem cells, characterized by abnormal differentiation and development of myeloid cells, manifested as ineffective hematopoiesis, refractory cytopenia, hematopoietic failure, and a high risk of transformation to acute myeloid leukemia (AML). Since the etiology and pathogenesis have not been fully elucidated, there is no unified, specific treatment plan for MDS. Chemotherapy, immunotherapy, thalidomide and its analogues, and hematopoietic stem cell transplantation are the most researched treatments for MDS. In this Special Issue, we highlight recent advances in our understanding of the pathophysiology of MDS and new therapeutic approaches, and we welcome submissions of original research papers and review papers.
Dr. Maria Cuzzola
Guest Editor
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Keywords
- myelodysplastic syndrome
- molecular pathology
- immunotherapy
- thalidomide and its analogues
- hematopoietic stem cell transplantation
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