Advanced Research in the Central Nervous System: Crosstalk between Systemic Inflammation and Neurodegenerative Disorders
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 3974
Special Issue Editor
Special Issue Information
Dear Colleagues,
With the aging population, the incidences of neurodegenerative diseases including Alzheimer’s and Parkinson’s diseases are exponentially increased. Risk factors including aging, metabolic disorders and surgical insults are involved in the progression in which systemic inflammation is a critical element among these factors. Under stress condition, our innate immune system is activated and constantly defending our body by putting it in a proinflammatory state. However, prolonged inflammatory response may result in significant damages in the central nervous system (CNS). Recent basic research pointed out that activation of innate immune response, ranging from the activation of innate immune cells to the release of inflammatory cytokines, can induce functional change to blood brain barrier, chronic neuroinflammatory response and subsequent neuronal dysfunction.
In this special issue, we aim to invite authors and investigators to submit and publish original research and review articles focusing on the interaction between systemic inflammation and neurodegenerative disorders. Studies on the molecular aspects of the crosstalk between innate immune response and neurodegeneration are welcome. Neuroprotective strategies targeting the innate immune response and systemic inflammation are also welcome. This issue will unveil the molecular mechanisms of how chronic inflammatory response will lead to the neurodegenerative disorders and facilitate the development of novel therapeutic strategies.
Dr. John Man Tak Chu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neurodegeneration
- systemic inflammation
- neuroinflammation
- innate immunity
- neuroprotection
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
