Inflammation and Vascular Biology in Regenerative Medicine

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 1759

Special Issue Editors


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Guest Editor
Department of Pharmacology and Regenerative Medicine, Center for Lung and Vascular Biology University of Illinois at Chicago, 909 South Wolcott Ave, COMRB 4020, Chicago, IL 60612, USA
Interests: vascular biology; Immunology; inflammation; macrophages; endothelial cells; injury and repair; regenerative medicine

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Guest Editor
Northwestern University Feinberg School of Medicine, Chicago, IL, USA
Interests: regulatory T cell; lung inflammation; viral pneumonia

Special Issue Information

Dear Colleagues,

This Special Issue, titled "Inflammation and Vascular Biology in Regenerative Medicine", aims to explore the intricate interplay between inflammation, vascular dynamics, and the emerging field of regenerative medicine. Inflammation plays a pivotal role in both initiating tissue injury and shaping repair and regenerative processes. The vascular system, with its role in delivering immune cells, nutrients, and growth factors, significantly influences these trajectories. This Special Issue welcomes original research, reviews, and studies that probe the multifaceted relationship between inflammation, vascular responses, and regenerative medicine across diverse contexts of tissue injury and regeneration. Topics of interest encompass the molecular mechanisms underlying inflammatory vascular injuries, the vascular orchestration of immune responses, immune-vascular interactions in tissue healing, the influence of immune and vascular factors (like cytokines, growth factors, and angiocrine factors) on injury and regeneration, and innovative therapeutic avenues targeting inflammation and the vascular system. By elucidating these connections, the Special Issue aims to foster insights and inspire novel strategies to enhance tissue repair and regeneration by leveraging the synergistic effects of inflammation and vascular biology.

Dr. Bisheng Zhou
Dr. Ruihua Ma
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inflammation
  • vascular biology
  • injury
  • repair
  • regeneration
  • immunity
  • macrophage
  • endothelial cells
  • cell signaling

Published Papers (1 paper)

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Review

17 pages, 1314 KiB  
Review
Roles of Macrophages and Endothelial Cells and Their Crosstalk in Acute Lung Injury
by Sara Osorio-Valencia and Bisheng Zhou
Biomedicines 2024, 12(3), 632; https://doi.org/10.3390/biomedicines12030632 - 13 Mar 2024
Viewed by 1499
Abstract
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), present life-threatening conditions characterized by inflammation and endothelial injury, leading to increased vascular permeability and lung edema. Key players in the pathogenesis and resolution of ALI are macrophages (Mφs) and [...] Read more.
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), present life-threatening conditions characterized by inflammation and endothelial injury, leading to increased vascular permeability and lung edema. Key players in the pathogenesis and resolution of ALI are macrophages (Mφs) and endothelial cells (ECs). The crosstalk between these two cell types has emerged as a significant focus for potential therapeutic interventions in ALI. This review provides a brief overview of the roles of Mφs and ECs and their interplay in ALI/ARDS. Moreover, it highlights the significance of investigating perivascular macrophages (PVMs) and immunomodulatory endothelial cells (IMECs) as crucial participants in the Mφ–EC crosstalk. This sheds light on the pathogenesis of ALI and paves the way for innovative treatment approaches. Full article
(This article belongs to the Special Issue Inflammation and Vascular Biology in Regenerative Medicine)
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