Advances in Pharmacotherapy of Alzheimer’s Disease
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 297
Special Issue Editor
Interests: Alzheimer’s disease; metals in medicine; PET imaging and diagnosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
After almost a century since its discovery, Alzheimer’s disease (AD) is still the most common cause of dementia, affecting over 40 million people worldwide. It is considered a major health hazard that mostly affects the population aged 65 years or older, though cases of younger populations affected by the disease have been reported (early-onset AD), with AD being the fifth leading cause of global death. There is currently no cure for it nor is there a clear understanding of the etiology of the disease. Several efforts have been made during these years to find diagnosis tools and treatments with limited clinical success. The most common treatments include immunotherapy targeting one of the hallmarks of the disease, the aggregation of amyloid beta plaques, antagonists of the N-methyl-D-aspartate (NMDA) receptors, and cholinesterase inhibitors. For this Special Issue, we encourage submissions related, but not limited, to the following topics: (1) research that highlights the recent advances related to the aforementioned treatment approaches; (2) research that presents new strategies that target different etiologies such as neuroinflammation, and what role they play in the big cascade of events that culminate in neuronal degeneration; and (3) research related to the role of metals in Alzheimer’s disease therapies.
Dr. Paulina Gonzalez
Guest Editor
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Keywords
- Alzheimer’s disease
- neuroinflammation
- neurodegeneration
- amyloid beta
- metals in Alzheimer’s disease
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