Pathogenesis and Novel Diagnostics in Juvenile Idiopathic Arthritis and Other Rheumatic Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 1343
Special Issue Editors
Interests: connective tissue diseases; pathology of the extracellular matrix; growth factors; juvenile idiopathic arthritis
Special Issues, Collections and Topics in MDPI journals
Interests: connective tissue diseases; pathology of the extracellular matrix; growth factors; systemic sclerosis; juvenile idiopathic arthritis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Paediatric rheumatic diseases refer to a heterogeneous collection of autoimmune or autoinflammatory forms of musculoskeletal, arthritic, and connective tissue disorders that can develop in childhood. The most common types of these diseases are juvenile idiopathic arthritis and other rheumatic diseases (such as dermatomyositis or systemic lupus erythematosus). These diseases can affect children of any age and any ethnic background, and being diagnosed too late or poorly treated may contribute to the disability of an afflicted child, due to disturbances in the structure and function of the osteoarticular and muscle system. Hence, the prompt detection of structural disorders of the articular cartilage would allow clinicians to initiate appropriate therapies, which is essential for the course of the arthropathy in question. Too late an application of appropriate treatment, resulting from the lack of specific diagnostic biomarkers, may result in the perpetuation of pathological changes in the motor system in patients, or the development of systemic disorders, especially in those with high disease activity who require an aggressive therapy.
It is therefore crucial that we continue to research the pathogenesis of paediatric rheumatic diseases, seeking new biomarkers of the diseases and effective therapeutic methods. We invite researchers to submit original works or review articles covering significant development in the pathogenesis of juvenile idiopathic arthritis and other rheumatic diseases, as well as novel diagnostic and therapeutic methods.
Prof. Dr. Katarzyna Winsz-Szczotka
Dr. Kornelia Kuźnik-Trocha
Guest Editors
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Keywords
- juvenile idiopathic arthritis
- juvenile dermatomyositis
- systemic lupus erythematosus
- musculoskeletal pain syndromes
- local and systemic scleroderma
- Kawasaki disease
- diagnosis and treatment
- biomarkers
- cartilage
- matrix
- inflammation
- extra-articular manifestations
- immune response
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