The Molecular Mechanisms of Hearing, Balance and Deafness
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 160
Special Issue Editor
2. Unit 728, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain
Interests: genomics of rare diseases; lysosomal diseases; autoinflammatory diseases; genetics of hearing impairment; animal models of disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Over the last 25 years, the molecular mechanisms underlying hearing and balance have begun to be unraveled by combining genetics, transcriptomics, protein interaction analyses, electrophysiology, systems biology, cellular and animal models, bioinformatic modelling and data science.
We know now that hearing is an intricate process in which mechantransduction is combined with diverse molecular specializations (such as active amplification, electromotility, adaptation, ribbon synapses, etc.) and a complex neural circuitry for the encoding and analysis of sound, with exquisite acuity and fidelity. The sense of balance participates from the same basic sensory cell types, transduction molecules and mechanisms underlying hearing, so that defects in this complex machinery may affect both hearing and balance.
Today, interventions targeting specific kinds of deafness have begun to be tested, with multiple clinical trials, employing different therapeutic approaches, currently underway.
In this Special Issue, we will welcome reviews and original articles relating to the processes of hearing and balance and any pathologies that affect these two senses, from a molecular point of view. The scope of topics includes (but is not limited to) sensory mechanisms, homeostatic processes, sound encoding, the pathogenesis and modelling of deafness and balance disorders, diagnostics and therapeutic interventions, and so on.
Dr. Francisco J. del Castillo
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- hearing
- balance
- deafness
- molecular mechanisms
- genetics
- transcriptomics
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
