Biosensors for 3D Engineered Cell Cultures
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 124
Special Issue Editors
Interests: hiPSC; human-induced pluripotent stem cells; human cardiac microtissues
Special Issue Information
Dear Colleagues,
Three-dimensional (3D) engineered cell cultures have revolutionized the field of bioengineering, offering more physiologically relevant models for studying the behavior of tissues, disease progression, and drug responses. However, the complexity of these systems poses significant challenges during the monitoring of cellular activities in real time and at a high resolution. Biosensors have emerged as transformative tools for the non-invasive, precise measurement of key biological parameters in 3D cultures, enabling advancements in tissue engineering, regenerative medicine, and personalized therapeutics.
This Special Issue of Bioengineering focuses on innovative biosensor technologies tailored for 3D engineered cell cultures. The scope of this Special Issue includes, but is not limited to, the following topics:
- The adaptations and adjustment of detection methods that have been originally developed for 2D cell cultures for use in a 3D context.
- The integration of biosensors for the real-time monitoring of cellular metabolism, oxygenation, pH, and electrophysiological activity.
- Advances in nanoscale and microfluidic biosensors for organoids, bioprinted tissues, and scaffold-based models.
- The development of wearable or implantable sensors for the long-term evaluation of 3D constructs.
- Biosensor-enabled high-throughput platforms for drug screening and toxicity testing in 3D cell cultures.
By exploring the synergy between biosensors and 3D cell culture systems, this Special Issue aims to present innovative approaches to addressing unmet challenges in tissue modeling and biomedical research. We welcome original research, reviews, and perspectives that advance this interdisciplinary field.
Dr. Verena Charwat
Dr. Antonia Silvestri
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biosensors
- 3D cell culture
- microengineering
- in vitro test systems
- microtissues
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
