Advancements in Bioelectronics: From Beaker to Wearable to Implantable Devices

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biosignal Processing".

Deadline for manuscript submissions: 20 September 2025 | Viewed by 3413

Special Issue Editor


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Guest Editor
School of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea
Interests: electrochemistry; biosensors; immunosensors; 2D-materials

Special Issue Information

Dear Colleagues,

Bioelectronics is a fast-expanding science that combines electronics with biology, with far-reaching implications for healthcare, biotechnology, and beyond. This Special Issue aims to highlight the most recent advances and innovations in bioelectronics, with a focus on wearable electronics, implantable electronics, "more than Moore" electronics, and the creation of bioelectronic devices.

Topics of interest include but are not limited to:

  • Wearable electronics: progress in wearable biosensors for continuous health monitoring.
  • Flexible and stretchable electronics for wearable applications.
  • Integration of sensors and actuators into wearable devices for individualized healthcare.
  • Wireless communication and power supply systems for wearable electronics.

Implantable Electronics:

  • Biocompatible materials and coatings for implantable devices.
  • Miniaturization and power efficiency for implanted electronics.
  • Bioresorbable and transient electronics for temporary implants.
  • Neural interfaces and brain–computer interfaces for therapeutic and scientific purposes.

"More Than Moore" Electronics:

  • Integrating biological components into electronic systems.
  • Bio-inspired design principles for technological equipment.
  • Nanoelectronics and nanomaterials for bioelectronic applications.
  • Bioelectronic circuits and systems for signal processing and control.

Bioelectronic Devices:

  • Electrochemical and photonic biosensors for medical diagnostics.
  • Bioelectronic implants for therapy and neurological modulation.
  • Rapid illness detection using lab-on-a-chip technology and point-of-care devices.
  • Biomedical imaging devices and approaches based on bioelectronic principles.

We invite academics, scientists, engineers, and practitioners from academia, business, and government institutions to submit original research papers, reviews, and comments on the latest discoveries and problems in bioelectronics.

This Special Issue intends to promote interdisciplinary collaboration, encourage debate, and speed up the translation of bioelectronics advances into practical applications that benefit human health and well-being.

Dr. Aneesh Koyappayil
Guest Editor

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Keywords

  • wearable biosensors
  • flexible and stretchable electronics
  • bioelectronic devices
  • implantable electronics
  • "more than moore" electronics
  • individualized healthcare

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Published Papers (2 papers)

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16 pages, 14753 KiB  
Article
Fabrication and Dielectric Validation of an Arm Phantom for Electromyostimulation
by Katja Uhrhan, Esther Schwindt and Hartmut Witte
Bioengineering 2024, 11(7), 724; https://doi.org/10.3390/bioengineering11070724 - 17 Jul 2024
Viewed by 1755
Abstract
Electromyostimulation (EMS) is an up-and-coming training method that demands further fundamental research regarding its safety and efficacy. To investigate the influence of different stimulation parameters, electrode positions and electrode sizes on the resulting voltage in the tissue, a tissue mimicking phantom is needed. [...] Read more.
Electromyostimulation (EMS) is an up-and-coming training method that demands further fundamental research regarding its safety and efficacy. To investigate the influence of different stimulation parameters, electrode positions and electrode sizes on the resulting voltage in the tissue, a tissue mimicking phantom is needed. Therefore, this study describes the fabrication of a hydrogel arm phantom for EMS applications with the tissue layers of skin, fat, blood and muscle. The phantom was dielectrically validated in the frequency range of 20 Hz to 100 Hz. We also conducted electromyography (EMG) recordings during EMS on the phantom and compared them with the same measurements on a human arm. The phantom reproduces the dielectric properties of the tissues with deviations ranging from 0.8% to more than 100%. Although we found it difficult to find a compromise between mimicking the permittivity and electrical conductivity at the same time, the EMS–EMG measurements showed similar waveforms (1.9–9.5% deviation) in the phantom and human. Our research contributes to the field of dielectric tissue phantoms, as it proposes a multilayer arm phantom for EMS applications. Consequently, the phantom can be used for initial EMS investigations, but future research should focus on further improving the dielectric properties. Full article
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20 pages, 7932 KiB  
Technical Note
HANDSON Hand: Strategies and Approaches for Competitive Success at CYBATHLON 2024
by Xuhui Hu, Fengkai Guo, Zhikai Wei, Dapeng Chen, Junfa Dai, Anran Li, Senhao Zhang, Mostafa Orban, Yao Tong, Cong Hu, Baoguo Xu, Hong Zeng, Aiguo Song, Kai Guo and Hongbo Yang
Bioengineering 2025, 12(3), 228; https://doi.org/10.3390/bioengineering12030228 - 24 Feb 2025
Viewed by 947
Abstract
A significant number of people with disabilities rely on assistive devices, yet these technologies often face limitations, including restricted functionality, inadequate user-centered design, and a lack of standardized evaluation metrics. While upper-limb prosthetics remain a key research focus, existing commercial solutions still fall [...] Read more.
A significant number of people with disabilities rely on assistive devices, yet these technologies often face limitations, including restricted functionality, inadequate user-centered design, and a lack of standardized evaluation metrics. While upper-limb prosthetics remain a key research focus, existing commercial solutions still fall short of meeting daily reliability and usability needs, leading to high abandonment rates. CYBATHLON integrates assistive technologies into daily living tasks, driving innovation and prioritizing user needs. In CYBATHLON 2024, the HANDSON hand secured first place in the arm prosthesis race, showcasing breakthroughs in human–robot integration. This paper presents the HANDSON hand’s design, core technologies, training strategies, and competition performance, offering insights for advancing multifunctional prosthetic hands to tackle real-world challenges. Full article
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