The Effects of Sleep Deprivation on Human Behavior and Neural Activity

A special issue of Behavioral Sciences (ISSN 2076-328X). This special issue belongs to the section "Psychiatric, Emotional and Behavioral Disorders".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 3508

Special Issue Editor


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Guest Editor
Health Sciences Institute, University of Veracruz, Xalapa 91050, Mexico
Interests: sleep function; neuronal plasticity; sleep deprivation; brain

Special Issue Information

Dear Colleagues,

Sleep is a fundamental physiological process that plays a crucial role in maintaining physical health, cognitive function, and emotional well-being. In recent years, there has been a growing recognition of the pervasive problem of sleep deprivation in modern society. The detrimental effects of sleep deprivation on human behavior and neural activity have far-reaching implications, touching upon various disciplines, including neuroscience, psychology, medicine, and public health.

Statement of Purpose: This special issue seeks to provide a comprehensive exploration of the impact of sleep deprivation on human behavior and neural activity. It aims to delve into the underlying mechanisms, consequences, and potential interventions related to this critical issue.

Relevance: The relevance of this topic cannot be overstated. In our fast-paced, 24/7 world, sleep deprivation has become increasingly prevalent, affecting individuals of all ages and backgrounds. This issue is particularly pertinent as it addresses a pressing concern that has direct implications for individual health and societal well-being.

Knowledge Gap: Despite the growing awareness of sleep deprivation's consequences, there remains a significant gap in our understanding of its effects on human behavior and neural activity. This special issue aims to bridge these knowledge gaps by synthesizing current research, identifying unexplored areas, and fostering new insights into sleep-related phenomena.

Interdisciplinary Nature: Sleep deprivation is a complex issue that demands an interdisciplinary approach. Researchers from diverse fields, including neuroscience, psychology, sleep medicine, and public health, will find value in the collaborative insights generated by this special issue. By bringing together experts from these disciplines, we aim to catalyze novel approaches to the study of sleep deprivation.

Timeliness: The timeliness of this special issue is evident as sleep deprivation continues to impact millions of individuals worldwide. Moreover, advances in neuroimaging, wearable technology, and behavioral research methods have provided unprecedented opportunities to investigate the intricacies of sleep deprivation's effects.

Potential Contributions: This special issue offers a platform for researchers to contribute groundbreaking findings, novel methodologies, and comprehensive reviews related to sleep deprivation. By pooling our collective knowledge, we aim to advance our understanding of how sleep deprivation influences human behavior and neural activity, potentially leading to improved interventions and policies.

Audience: The target audience for this special issue includes researchers, clinicians, educators, policymakers, and anyone interested in the intersection of sleep, behavior, and neuroscience. We anticipate that the research presented here will inform both scientific discourse and practical strategies for managing and mitigating sleep deprivation.

Methodological Diversity: We encourage submissions employing a diverse array of research methods, including but not limited to experimental studies, clinical investigations, neuroimaging, surveys, longitudinal studies, and computational modeling. Such diversity will provide a more comprehensive understanding of sleep deprivation's multifaceted impact.

Potential Impact: The research presented in this special issue has the potential to drive significant advancements in our approach to sleep health. By shedding light on the neural underpinnings of sleep deprivation and its consequences on behavior, we may uncover innovative avenues for therapeutic interventions and public health initiatives aimed at promoting healthier sleep patterns.

Conclusion: In conclusion, this special issue on "The Impact of Sleep Deprivation on Human Behavior and Neural Activity" addresses a critical and timely subject with far-reaching implications. We invite researchers to contribute their expertise and insights to enrich our understanding of sleep deprivation and its consequences. Together, we can pave the way for improved sleep health and well-being for individuals and societies worldwide.

Call to Action: We encourage researchers to submit their original research, reviews, and perspectives to this special issue, fostering a collaborative and multidisciplinary dialogue on sleep deprivation's impact. Together, we can advance the field and develop evidence-based strategies to mitigate the adverse effects of sleep deprivation on human behavior and neural activity.

Prof. Dr. Fabio Garcia-Garcia
Guest Editor

Manuscript Submission Information

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Keywords

  • sleep function
  • neuronal firing
  • neuronal plasticity
  • learning
  • cognitive impairment
  • sleep loss

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Published Papers (2 papers)

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Research

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26 pages, 1424 KiB  
Article
Enhancing Mental Health and Cognitive Functioning in Victims of Violence: Cognitive Behavioral Therapy for Sleep Disorders Among Journalists, Human Rights Defenders, and Relatives of Disappeared Persons in Mexico City
by Araceli Martínez-Moreno, Guadalupe Terán-Pérez, Yoaly Arana-Lechuga, Javier Velázquez-Moctezuma, Oscar Sánchez-Escandón, Daniela Guarneros-Roniger and Roberto E. Mercadillo
Behav. Sci. 2025, 15(4), 530; https://doi.org/10.3390/bs15040530 - 15 Apr 2025
Viewed by 1359
Abstract
In Mexico, pervasive violence, forced disappearances, and homicides have deeply impacted certain groups, particularly journalists, activists, and human rights defenders, who are at high risk of victimization. While these groups receive state support for physical and legal safety, mental health and sleep-focused interventions [...] Read more.
In Mexico, pervasive violence, forced disappearances, and homicides have deeply impacted certain groups, particularly journalists, activists, and human rights defenders, who are at high risk of victimization. While these groups receive state support for physical and legal safety, mental health and sleep-focused interventions remain insufficient. Collaborating with a Mexico City-based institution supporting human rights defenders and journalists, we conducted a psychometric assessment of 47 individuals affected by violence. Results showed that 80% exhibited symptoms of post-traumatic stress disorder, 25.5% showed depression, and 57.4% displayed anxiety; 95.7% reported poor sleep quality based on the Pittsburgh Sleep Quality Index. In a second phase, neuropsychological tests and polysomnographic recordings identified cognitive impairments in attention, memory, and decision-making in some participants, along with sleep disorders such as insomnia, primary snoring, obstructive sleep apnea, and bruxism. A third phase introduced Cognitive Behavioral Therapy for insomnia, nightmares, and circadian rhythm issues. Results showed improvements in sleep quality, total sleep time, and a reduction in depression, anxiety, and post-traumatic stress disorder symptoms. This approach suggests that treating sleep issues in high-risk populations can improve mental health. Full article
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15 pages, 544 KiB  
Review
Sleep Loss and Substance Use Disorders: An Issue from Adolescents to Adults
by Ana Clementina Equihua-Benítez, Rodolfo Espinoza-Abad and Fabio García-García
Behav. Sci. 2025, 15(2), 220; https://doi.org/10.3390/bs15020220 - 15 Feb 2025
Viewed by 1086
Abstract
Unsatisfactory sleep is a worldwide concern, as evidenced by the high prevalence of insomnia symptoms and diagnosis in the general population, and an issue that has also risen among adolescents. These circumstances are a cause of worry due to, among other factors, the [...] Read more.
Unsatisfactory sleep is a worldwide concern, as evidenced by the high prevalence of insomnia symptoms and diagnosis in the general population, and an issue that has also risen among adolescents. These circumstances are a cause of worry due to, among other factors, the observed bidirectional association of sleep disturbances and the risk of substance use disorder development. In this regard, across the globe, several reports indicate that substance consumption is at an all-time high, with alcohol, nicotine, and cannabis leading the charts. Additionally, the age of onset has dropped, with reports suggesting that first contact is usually during adolescence. Although the nature of the link between poor sleep and substance use disorder development is still not fully understood, it is possible that an overactive orexinergic system could play a role, as it has been observed that treatment with orexinergic antagonists improves insomnia symptoms and that postmortem studies show an increase in orexin immunoreactive neurons in sections obtained from habitual opioid consumers. We further argue that it is during adolescence that this maladaptive loop can be established, priming for the development of substance use disorders. Full article
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