1,2,4-Triazine Derivatives and Their Biological Applications
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".
Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 799
Special Issue Editor
Interests: medicinal chemistry; medicinal and pharmaceutical chemistry; synthetic organic chemistry; heterocyclic chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
1,2,4-Triazine is one of the best known heterocyclic systems and is still very popular among scientists designing new structures with biological activity. This popularity is due to its chemical properties—more electron-deficient system than pyridine, pyrimidine, pyrazine, or pyridazine—which have been used to construct a variety of mono and fused derivatives involved in diverse structure–activity relationship studies. A number of literature reports indicate the widespread use of this heterocyclic system, which is still a valuable substrate for many studies, including the design of new molecules with targeted biological activity. For this purpose, the triazine scaffold can be flanked with other polycyclic moieties or used as a ligand for a heterobimetallic complex.
This Special Issue of Applied Sciences, entitled “Triazine Derivatives and Their Biological Applications”, will deal with the synthetic methods developed for the preparation of 1,2,4-triazine derivatives, but also with aspects such as the collection of new structural information or the development of novel applications.
Prof. Dr. Mariusz Mojzych
Guest Editor
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Keywords
- 1,2,4-triazine
- fused 1,2,4-triazine
- synthesis
- molecular structure
- biological activity
- applications
- structure–activity relationship
- X-ray analysis
- reactivity of 1,2,4-triazine
- chemical properties
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