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Advances in Biomimetic Design and Materials
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Advances in Biomimetic Design and Materials

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (20 March 2025) | Viewed by 2815

Special Issue Editors

Prof. Dr. Hernando S. Salapare III

E-Mail Website
Guest Editor
Biomaterials-Biointerfaces Group, Université de Haute-Alsace, CNRS, IS2M, UMR 7361, F-68100 Mulhouse, France
Interests: bioinspired materials; biomaterials; protein adsorption; plasma-processed materials; special wettabilities; functional polymers; surface functionalization; aerospace materials
Special Issues, Collections and Topics in MDPI journals
Dr. Carole Arnold

E-Mail Website
Guest Editor
CNRS, Université de Haute-Alsace, IS2M, UMR 7361, F-68100 Mulhouse, France
Interests: protein auto-assemblies; biomaterials; cell fate determination
Dr. Katia Carneiro

E-Mail Website1 Website2
Guest Editor
Department of Histology and Embryology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Interests: biomaterials; oncobiology; developmental and regenerative biology

Special Issue Information

Dear Colleagues,

Nature has provided a variety of inspiration for designs and materials with outstanding physical and chemical qualities. With the help of these inspirations, we want to execute bioinspired engineering that will be advantageous to several facets of our society. As an example, different types of sensors (chemical or electronic) that are helpful in the disciplines of health and robotics are created by simulating the five basic human senses. Another illustration is the bioinspiration used in the development of photocatalytic materials from the photosynthesis of plants.

The development of bioinspired materials and designs has surged in recent years and this Special Issue aims to collect these advances. Typical topics such as biomimetics, biomimicry, biomimicry architecture, bioinspired materials, bio-inspired computing, biomimetic proteins, biomechanics and biorobotics, biomaterials, biopolymers, catalytic systems and materials, design, green chemistry, materials, nanomaterials, nature, regenerative materials, sensors, smart materials, sustainability, and other related topics are very much welcome in this Special Issue. For physicists, chemists, biologists, engineers, and other scientists to collaborate and contribute to the advancements in this multidisciplinary subject, we think that this Issue will be an excellent venue.

Prof. Dr. Hernando S. Salapare III
Dr. Carole Arnold
Dr. Katia Carneiro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomimetics
  • biomimicry
  • biomimicry architecture
  • bioinspired materials
  • bioinspired computing
  • biomimetic proteins
  • biomechanics and biorobotics
  • biomaterials
  • biopolymers
  • catalytic systems
  • design
  • green chemistry
  • materials
  • nanomaterials
  • nature
  • regenerative materials
  • sensors
  • smart materials
  • sustainability

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

15 pages, 5293 KiB  
Article
Biomechanical Optimization of Lumbar Fusion Cages with a Porous Design: A Finite Element Analysis
by Chenkai Zhu, Kan Deng, Zhenzong Shao and Yong Wang
Appl. Sci. 2025, 15(10), 5384; https://doi.org/10.3390/app15105384 - 12 May 2025
Viewed by 190
Abstract
Lumbar interbody fusion (LIF) is a standard treatment for spinal instability, yet postoperative subsidence and adjacent segment degeneration (ASD) remain critical challenges. This study evaluates the biomechanical efficacy of personalized porous fusion cages—featuring Gyroid (G-Cage) and Voronoi (V-Cage) architectures—against classic (C-Cage) and personalized [...] Read more.
Lumbar interbody fusion (LIF) is a standard treatment for spinal instability, yet postoperative subsidence and adjacent segment degeneration (ASD) remain critical challenges. This study evaluates the biomechanical efficacy of personalized porous fusion cages—featuring Gyroid (G-Cage) and Voronoi (V-Cage) architectures—against classic (C-Cage) and personalized (P-Cage) designs, aiming to enhance stability and mitigate subsidence risks. A finite element model of the L3–L4 segment, derived from CT scans of a healthy male volunteer, was developed to simulate six motion modes (compression, rotation, flexion, extension, and left/right bending). Biomechanical parameters, including range of motion (ROM), cage stress, endplate stress, and displacement, were analyzed. The results demonstrated that the V-Cage exhibited superior performance, reducing ROM by 51% in extension, cage stress by 41.7% in compression, and endplate stress by 63.7% in right bending compared to the C-Cage. The porous designs (G-Cage, V-Cage) exhibited biomimetic stress distribution and minimized micromotion, which was attributed to their trabecular-like architectures. These findings highlight the Voronoi-based porous cage as a biomechanically optimized solution, offering enhanced stability and reduced subsidence risk when compared to classic implants. The study underscores the potential of patient-specific porous designs in advancing LIF outcomes, warranting further clinical validation to translate computational insights into practical applications. Full article
(This article belongs to the Special Issue Advances in Biomimetic Design and Materials)
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13 pages, 4862 KiB  
Article
Lymphedema Surgical Treatment Using BioBridgeTM: A Preliminary Experience
by Maurizio Cè, Andrea Menozzi, Massimo Soresina, Denisa Giardini, Carlo Martinenghi and Michaela Cellina
Appl. Sci. 2023, 13(20), 11571; https://doi.org/10.3390/app132011571 - 23 Oct 2023
Cited by 1 | Viewed by 1953
Abstract
Lymphedema treatment has traditionally been based on conservative therapies. In recent years, the introduction of two microsurgical techniques—venolymphatic anastomoses and lymph-node transplantation—have revolutionized the therapeutic approach to this disease. However, these surgical techniques only provide a partial volume reduction, and thus, they require [...] Read more.
Lymphedema treatment has traditionally been based on conservative therapies. In recent years, the introduction of two microsurgical techniques—venolymphatic anastomoses and lymph-node transplantation—have revolutionized the therapeutic approach to this disease. However, these surgical techniques only provide a partial volume reduction, and thus, they require further improvement. A new device called BioBridgeTM, an implantable biocompatible and biodegradable mesh, made up of aligned nanofibrillar collagen scaffolds that mimic the collagen matrix, could significantly improve the benefits of these surgical strategies, favoring lymphatic regeneration. In this article, we describe our experience with three patients affected by primary lymphedema, two treated with a lymph-node transplant, and one with venolymphatic anastomosis. All interventions involved the placement of nanocollagen scaffolds. With each patient, non-contrast magnetic resonance lymphography was performed for surgical planning and there was an imaging and a clinical follow-up at 1 year. All patients showed a significant reduction in the affected areas with the demonstration of new lymphatic vessels at MR imaging follow-up. This was a preliminary experience, and it showed the potential benefit of positioning nonfibrillar scaffolds in combination with other microsurgical therapies for lymphedema. Full article
(This article belongs to the Special Issue Advances in Biomimetic Design and Materials)
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