Advanced Point-of-Care Diagnostics: Integrating Engineering and Biosciences for Rapid Clinical Solutions
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 21
Special Issue Editor
Interests: technology in healthcare; chronic diseases and quality of life; personalized medicine; cardiopulmonary diseases; machine learning in healthcare efficiency
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue, entitled “Advanced Point-of-Care Diagnostics: Integrating Engineering and Biosciences for Rapid Clinical Solutions”, seeks to analyze innovations within the scope and boundaries of bioengineering, biosciences, and clinical medicine. The objective is to focus on “real-world” diagnosis and management of diseases in the context of previously neglected and/or resource-sparse regions. The global rise in constant health threats, such as the outbreak of infective diseases, chronic health issues, and lack of healthcare equity, continues to present the overwhelming need for effective, economical, and timely diagnostic devices to be a global concern.
Engineering innovations in biosensors, microfluidics, CRISPR, and AI have changed the architecture and workflow common in testing and diagnostic point-of-care (POC) devices. These technologies allow for accurate and timely testing to be carried out away from the central laboratory so that health workers can help patients at the bedside, the primary health care center, or even remote areas. This Special Issue aims to highlight primary responses focused on basic and implemented clinical problem-solving from the point of view of engineering and laboratory diagnostics towards the implementation of existing devices and all the conditions necessary for their use in practice.
As a guideline, we invite inputs that concentrate on, but are not limited to, any of the following topics:
- Next-generation biosensors for the detection of infectious diseases or metabolic disorders and their biomarkers.
- Microfluidic and lab-on-a-chip technologies for low-cost and multiplexed assays.
- AI imaging tools for diagnostics such as smartphones, predictive analytics, and clinical decision support systems.
- CRISPR and molecular diagnostics for the rapid and portable detection of pathogens.
- Wearable and remote monitoring devices for chronic disease management.
- Global outreach strategies, which include device ruggedness, adaptability to the local climate and culture, and design inclusivity.
This Special Issue promotes and focuses on transnational research with an emphasis on clinical validation, usability studies, and stakeholder engagement from resource-constrained settings. We hope to consolidate researchers, clinicians, engineers, and policymakers for interdisciplinary dialogue with the goal of facilitating the implementation of POC technologies designed to tackle healthcare disparity, improve patient outcomes, and strengthen global health resilience.
You are welcome to submit your original work, comprehensive literature reviews, and case studies that examine the impact of advanced diagnostics on the frontline of care delivery.
Undoubtedly, we can work towards a future where no one is deprived of life-saving diagnostics due to geographical or resource limitations.
Dr. Gheorghe Nicusor Pop
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- point-of-care diagnostics
- biosensors
- microfluidics
- artificial intelligence (AI) in healthcare
- CRISPR diagnostics
- rapid diagnostic testing
- disease detection
- clinical translation
- global health technologies
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