Nanocarrier-Based Drug Delivery for Bioavailability Improvement
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 18
Special Issue Editor
Interests: drug delivery; nanoparticles; formulation; analytical chemistry; LC-MS/MS; pharmacokinetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent decades, nanocarrier-based drug delivery systems have gained significant attention as a promising strategy to overcome challenges related to the poor solubility, limited absorption, and suboptimal bioavailability of many therapeutic agents. By enhancing pharmacokinetic profiles and enabling more targeted delivery, nanocarriers have shown the potential to significantly improve therapeutic outcomes across a wide spectrum of diseases. Various nanocarrier platforms have been developed and extensively studied, including micelles, nanoemulsions, liposomes, polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, and inorganic nanoparticles. These systems have been employed to deliver a wide range of therapeutic agents, such as small-molecule drugs, peptides, proteins, and nucleic acids.
Some of these nanocarrier-based formulations have successfully advanced to clinical application and have been approved as nanomedicines, underscoring their translational potential. However, there remains a critical need for further development, optimization, and innovation in the field with an aim to enhance drug bioavailability. Thorough preclinical studies are needed to better understand the factors influencing absorption, tissue distribution, and therapeutic efficacy.
In this Special Issue, we welcome reviews and original research focused on the development, characterization, and application of nanocarriers for drug delivery, with an emphasis on improving bioavailability and therapeutic performance. Topics of interest include novel nanocarrier design strategies, formulation optimization, in vitro and in vivo performance, and their use in the treatment of diverse diseases. We aim to showcase the latest advances in the field and foster further innovation toward more effective and clinically viable nanomedicine platforms.
Dr. Van-An Duong
Guest Editor
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Keywords
- nanocarriers
- bioavailability
- pharmacokinetic
- micelles
- nanoemulsions
- liposomes
- solid lipid nanoparticles
- nanostructured lipid carriers
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