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AppliedChem
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Feature Papers in AppliedChem, 2nd Edition
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Feature Papers in AppliedChem, 2nd Edition

A special issue of AppliedChem (ISSN 2673-9623).

Deadline for manuscript submissions: closed (20 April 2026) | Viewed by 3227

Special Issue Editor

Prof. Dr. Jason Love

E-Mail Website1 Website2
Guest Editor
School of Chemistry, University of Edinburgh, Edinburgh EH9 3FJ, UK
Interests: sustainable chemistry; f-element compounds; ligand design; extraction and recycling of metals
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This is a collection of top-quality papers published in open access form by editorial board members, or those invited by the editorial office and the Editor-in-Chief. The papers should be long research papers (or review papers) with a full and detailed summary of the author’s own work carried out so far.

Prof. Dr. Jason Love
Guest Editor

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Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. AppliedChem is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inorganic chemistry
  • catalysis
  • chemical process
  • sustainable chemistry
  • metal compounds

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Published Papers (3 papers)

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Research

16 pages, 5313 KB  
Article
Toxicity Screening of Wildfire-Impacted Residential Soils Using a Multi-Stress Escherichia coli Bioluminescent Bioreporter Panel
by Liron Saar Makrabi, Gal Carmeli, Abraham Abbey Paul and Robert S. Marks
AppliedChem 2026, 6(2), 30; https://doi.org/10.3390/appliedchem6020030 - 2 May 2026
Viewed by 290
Abstract
Wildfires that destroy residential infrastructure can generate chemically complex soil contamination; however, post-fire screening is often limited and does not directly reflect biological hazards. Herein, we integrated a multi-stress lux-based whole-cell bioreporter panel of genetically engineered Escherichia coli strains with non-targeted LC-MS [...] Read more.
Wildfires that destroy residential infrastructure can generate chemically complex soil contamination; however, post-fire screening is often limited and does not directly reflect biological hazards. Herein, we integrated a multi-stress lux-based whole-cell bioreporter panel of genetically engineered Escherichia coli strains with non-targeted LC-MS profiling to obtain a mechanism-informed assessment of soils collected from a residential property impacted by the January 2025 Los Angeles wildfires. The bioreporter panel resolved heterogeneous and statistically significant stress signatures across the analyzed samples. In particular, extracts from U3–U5 produced selective suppression of the membrane and fatty acid biosynthesis bioreporters, along with reduced growth. In contrast, extract U5 induced a proteotoxic heat-shock response signature. In parallel, non-targeted LC-MS detected 1813 chemical features and enabled the putative annotation of a subset of signals consistent with combustion-derived organics and reactive electrophiles, providing a chemical context for the observed bioassay fingerprints. The integrated workflow provides mechanism-resolved hazard triage within 48 h, as implemented herein (24 h elutriate preparation plus up to 20 h microplate kinetics), supporting the prioritization of hotspots for confirmatory analysis, remediation, and risk assessment. Full article
(This article belongs to the Special Issue Feature Papers in AppliedChem, 2nd Edition)
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17 pages, 4578 KB  
Article
Hydrothermal Synthesis of FAU-Type Zeolite NaX Using Ladle Slag and Waste Aluminum Cans
by Borislav Barbov, Hristina Lazarova, Liliya Tsvetanova and Aleksandar Nikolov
AppliedChem 2026, 6(1), 12; https://doi.org/10.3390/appliedchem6010012 - 3 Feb 2026
Viewed by 1032
Abstract
This study explores a sustainable synthesis route for FAU-type zeolite X using acid-treated ladle slag as a silicon source and waste aluminum cans as an alternative aluminum precursor. Conventional zeolite synthesis relies on high-purity reagents, which are costly and environmentally intensive to produce. [...] Read more.
This study explores a sustainable synthesis route for FAU-type zeolite X using acid-treated ladle slag as a silicon source and waste aluminum cans as an alternative aluminum precursor. Conventional zeolite synthesis relies on high-purity reagents, which are costly and environmentally intensive to produce. Previous research has rarely addressed the valorization of ladle slag and metallic aluminum waste for zeolite formation, leaving their potential largely unexplored. The study focuses on the effective utilization of industrial and post-consumer wastes—acid-treated ladle slag and aluminum cans—as precursors for FAU-type NaX zeolite, demonstrating their feasibility as alternative silicon and aluminum sources. Here, zeolite X was synthesized hydrothermally from treated slag combined with either dissolved aluminum cans and commercial sodium aluminate at 90 °C for 6 h. FAU-type zeolite X was successfully synthesized using both aluminum sources, with a SiO2/Al2O3 ratio of approximately 1.4. The results demonstrate that waste-derived precursors can effectively replace conventional chemicals, yielding predominantly NaX zeolite with high crystallinity and minor NaA impurity (as observed by XRD), with experimental yields of 1.47 g for aluminum cans and 1.266 g for sodium aluminate. The obtained zeolite X samples were structurally and texturally characterized by XRD, FTIR, XRF, BET surface area analysis, and thermogravimetric analysis (TG). Full article
(This article belongs to the Special Issue Feature Papers in AppliedChem, 2nd Edition)
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15 pages, 1430 KB  
Article
Advances in Paper Spray Mass Spectrometry (PS-MS) for On-Site Harm Reduction Drug Checking and Illicit Supply Surveillance
by Taelor M. Zarkovic, Lucas R. Abruzzi, Collin Kielty, Bruce Wallace, Dennis K. Hore and Chris G. Gill
AppliedChem 2025, 5(4), 36; https://doi.org/10.3390/appliedchem5040036 - 1 Dec 2025
Cited by 1 | Viewed by 1269
Abstract
Harm reduction drug checking utilizing paper spray mass spectrometry (PS-MS) has been the focus of ongoing research since 2017 and has seen many refinements. The presented work is the result of this research and has led to the public-facing PS-MS use for on-site [...] Read more.
Harm reduction drug checking utilizing paper spray mass spectrometry (PS-MS) has been the focus of ongoing research since 2017 and has seen many refinements. The presented work is the result of this research and has led to the public-facing PS-MS use for on-site drug checking in Victoria, BC. Included are the improved methods and approaches required to develop and implement PS-MS as an on-site drug checking technology. Critical details regarding appropriate direct mass spectrometry tune and calibration suites required to avoid isobaric interferences, calibration details, quality control strategies, detailed MS scan approaches to implement rapid drug tests, as well as future work considerations are presented. The PS-MS method presented currently directly quantifies 107 targeted drugs in a two-minute measurement, and can be easily adapted to include additional new targets that appear in the unregulated drug supply that are detected by either low or high resolution PS-MS. The presented methodologies provide a framework to assist those interested in implementing PS-MS to reduce harms from the toxic drug supply, but will have value for those developing rapid, quantitative drug testing for other applications. Full article
(This article belongs to the Special Issue Feature Papers in AppliedChem, 2nd Edition)
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