As all of the articles published in our journal are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below.

1. “PI3K–AKT-Targeting Breast Cancer Treatments: Natural Products and Synthetic Compounds”
by Yeqin Yuan, Huizhi Long, Ziwei Zhou, Yuting Fu and Binyuan Jiang
Biomolecules 2023, 13(1), 93; https://doi.org/10.3390/biom13010093
Full text available online: https://www.mdpi.com/2218-273X/13/1/93

2. “The Multifaceted Role of Aquaporin-9 in Health and Its Potential as a Clinical Biomarker”
by Inês V. da Silva, Sabino Garra, Giuseppe Calamita and Graça Soveral
Biomolecules 2022, 12(7), 897; https://doi.org/10.3390/biom12070897
Full text available online: https://www.mdpi.com/2218-273X/12/7/897

3. “Macrophages in Skin Wounds: Functions and Therapeutic Potential”
by Seen Ling Sim, Snehlata Kumari, Simranpreet Kaur and Kiarash Khosrotehrani
Biomolecules 2022, 12(11), 1659; https://doi.org/10.3390/biom12111659
Full text available online: https://www.mdpi.com/2218-273X/12/11/1659

4. “Rosmarinic Acid and Related Dietary Supplements: Potential Applications in the Prevention and Treatment of Cancer”
by Jiachao Zhao, Liwei Xu, Di Jin, Yu Xin, Lin Tian, Tan Wang, Daqing Zhao, Zeyu Wang and Jing Wang
Biomolecules 2022, 12(10), 1410; https://doi.org/10.3390/biom12101410
Full text available online: https://www.mdpi.com/2218-273X/12/10/1410

5.  “Vitamin D3 Stimulates Proliferation Capacity, Expression of Pluripotency Markers, and Osteogenesis of Human Bone Marrow Mesenchymal Stromal/Stem Cells, Partly through SIRT1 Signaling”
by Ana Borojević, Aleksandra Jauković, Tamara Kukolj, Slavko Mojsilović, Hristina Obradović, Drenka Trivanović, Milena Živanović, Željko Zečević, Marija Simić, Borko Gobeljić et al.
Biomolecules 2022, 12(2), 323; https://doi.org/10.3390/biom12020323
Full text available online: https://www.mdpi.com/2218-273X/12/2/323

6. “Cytochromes P450 of Caenorhabditis elegans: Implication in Biological Functions and Metabolism of Xenobiotics”
by Lucie Larigot, Daniel Mansuy, Ilona Borowski, Xavier Coumoul and Julien Dairou
Biomolecules 2022, 12(3), 342; https://doi.org/10.3390/biom12030342
Full text available online: https://www.mdpi.com/2218-273X/12/3/342

7. “Progress in Investigational Agents Targeting Serotonin-6 Receptors for the Treatment of Brain Disorders”
by Pradeep Jayarajan Ramakrishna, Anil Shinde, Abdul Rasheed Mohammed, Venkata Ramalingayya Grandhi, Vijay Benade, Vinod Kumar Goyal, Renny Abraham, Venkat Jasti and Jeffrey Cummings
Biomolecules 2023, 13(2), 309; https://doi.org/10.3390/biom13020309
Full text available online: https://www.mdpi.com/2218-273X/13/2/309

8. “The Complex Biological Effects of Pectin: Galectin-3 Targeting as Potential Human Health Improvement?”
by Lucas de Freitas Pedrosa, Avraham Raz and João Paulo Fabi
Biomolecules 2022, 12(2), 289; https://doi.org/10.3390/biom12020289
Full text available online: https://www.mdpi.com/2218-273X/12/2/289

9. “Biomarker Characterization and Prediction of Virulence and Antibiotic Resistance from Helicobacter pylori Next Generation Sequencing Data”
by Joana S. Vital, Luís Tanoeiro, Ricardo Lopes-Oliveira and Filipa F. Vale
Biomolecules 2022, 12(5), 691; https://doi.org/10.3390/biom12050691
Full text available online: https://www.mdpi.com/2218-273X/12/5/691

10. “Inhibitors of the Cancer Target Ribonucleotide Reductase, Past and Present”
by Sarah E. Huff, Jordan M. Winter and Chris G. Dealwis
Biomolecules 2022, 12(6), 815; https://doi.org/10.3390/biom12060815  
Full text available online: https://www.mdpi.com/2218-273X/12/6/815