- Article
The NR4A Orphan Receptor Modulator C-DIM12 Selectively Alters Inflammatory Mediators in Myeloid Cells
- Sarah Aldhafiri,
- Mariam Marai,
- Mohamed Ismaiel,
- Brenda Murphy,
- Hugh E. Giffney,
- Thomas J. Hall,
- Evelyn P. Murphy,
- Eoin P. Cummins and
- Daniel Crean
Orphan nuclear receptor subfamily 4A (NR4A) are key regulators of inflammatory responses, largely by their interactions with NF-κB. Over the last decade, several NR4A modulators have been developed, and they are showing potential as therapeutic...