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SynBio, Volume 3, Issue 3

2025 September - 5 articles

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Articles (5)

  • Review
  • Open Access
1,739 Views
22 Pages

Unlocking MSC Potential: Metabolic Reprogramming via Synthetic Biology Approaches

  • Natalia Trufanova,
  • Oleh Trufanov and
  • Oleksandr Petrenko

17 September 2025

Metabolic engineering of mesenchymal stem/stromal cells (MSCs) represents a compelling frontier for advanced cellular therapies, enabling the precise tuning of their biological outputs. This feature paper examines the critical role of engineered cult...

  • Perspective
  • Open Access
1,915 Views
10 Pages

Silicon Is the Next Frontier in Plant Synthetic Biology

  • Aniruddha Acharya,
  • Kaitlin Hopkins and
  • Tatum Simms

3 August 2025

Silicon has a striking similarity to carbon and is found in plant cells. However, there is no specific role that has been assigned to silicon in the life cycle of plants. The amount of silicon in plant cells is species specific and can reach levels c...

  • Review
  • Open Access
2 Citations
7,371 Views
34 Pages

A Guide in Synthetic Biology: Designing Genetic Circuits and Their Applications in Stem Cells

  • Karim S. Elnaggar,
  • Ola Gamal,
  • Nouran Hesham,
  • Sama Ayman,
  • Nouran Mohamed,
  • Ali Moataz,
  • Emad M. Elzayat and
  • Nourhan Hassan

22 July 2025

Stem cells, unspecialized cells with regenerative and differentiation capabilities, hold immense potential in regenerative medicine, exemplified by hematopoietic stem cell transplantation. However, their clinical application faces significant limitat...

  • Review
  • Open Access
6,440 Views
27 Pages

Cell-Free Protein Synthesis Reactor Formats: A Brief History and Analysis

  • Dallin M. Chipman,
  • Anna C. Woolley,
  • Davu N. Chau,
  • William A. Lance,
  • Joseph P. Talley,
  • Tyler P. Green,
  • Benjamin C. Robbins and
  • Bradley C. Bundy

1 July 2025

Cell-free protein synthesis (CFPS) has transformed protein production capabilities by eliminating cellular constraints, enabling the rapid expression of difficult-to-produce proteins in an open, customizable environment. As CFPS applications expand f...

  • Review
  • Open Access
1 Citations
4,948 Views
21 Pages

Plant Transformation and Genome Editing for Precise Synthetic Biology Applications

  • Sharathchandra Kambampati,
  • Pankaj K. Verma and
  • Madhusudhana R. Janga

27 June 2025

Synthetic biology (SynBio) is an emerging interdisciplinary field that applies engineering principles to the design and construction of novel biological systems or the redesign of existing natural systems for new functions. As autotrophs with complex...

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SynBio - ISSN 2674-0583