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Open AccessArticle
Same Day Microfluidics: From Design to Device in Under Three Hours
by
Raymond J. Arebalo
Raymond J. Arebalo
,
Augustin J. Sanchez
Augustin J. Sanchez
and
Nathan Tompkins
Nathan Tompkins *
Physics Department, Wabash College, Crawfordsville, IN 47933, USA
*
Author to whom correspondence should be addressed.
Nanomanufacturing 2025, 5(3), 9; https://doi.org/10.3390/nanomanufacturing5030009 (registering DOI)
Submission received: 2 April 2025
/
Revised: 28 May 2025
/
Accepted: 20 June 2025
/
Published: 27 June 2025
Abstract
Microfluidic devices are used in numerous scientific fields and research areas, but device fabrication is still a time- and resource-intensive process largely confined to the cleanroom or a similarly well-equipped laboratory. This paper presents a method to create microfluidic devices in under three hours using the silicone polymer polydimethylsiloxane (PDMS) and a laser cut positive master using PDMS double casting without a cleanroom or other large capital equipment. This method can be utilized by an undergraduate student with minimal training in a laboratory with a modest budget. This paper presents “Same Day Microfluidics” as a fabrication method accessible to research groups not currently fabricating their own microfluidic devices and as an option for established research groups to more quickly create prototype devices. The method is described in detail with timing, materials, and technical considerations for each step and demonstrated in the context of a Y-channel coflow device.
Share and Cite
MDPI and ACS Style
Arebalo, R.J.; Sanchez, A.J.; Tompkins, N.
Same Day Microfluidics: From Design to Device in Under Three Hours. Nanomanufacturing 2025, 5, 9.
https://doi.org/10.3390/nanomanufacturing5030009
AMA Style
Arebalo RJ, Sanchez AJ, Tompkins N.
Same Day Microfluidics: From Design to Device in Under Three Hours. Nanomanufacturing. 2025; 5(3):9.
https://doi.org/10.3390/nanomanufacturing5030009
Chicago/Turabian Style
Arebalo, Raymond J., Augustin J. Sanchez, and Nathan Tompkins.
2025. "Same Day Microfluidics: From Design to Device in Under Three Hours" Nanomanufacturing 5, no. 3: 9.
https://doi.org/10.3390/nanomanufacturing5030009
APA Style
Arebalo, R. J., Sanchez, A. J., & Tompkins, N.
(2025). Same Day Microfluidics: From Design to Device in Under Three Hours. Nanomanufacturing, 5(3), 9.
https://doi.org/10.3390/nanomanufacturing5030009
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