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Macromol, Volume 5, Issue 4

2025 December - 18 articles

Cover Story: Collagen- and gelatin-based hydrogels have gained attention in numerous applications, including biomedical, food, pharmaceutical, and environmental applications. Probing the rheological properties of these gels provides deeper and more accurate insights into their structure, physical properties, stability, and release profiles. This review provides an in-depth evaluation of the factors affecting the mechanical strength/rheology of collagen- and gelatin-based hydrogels, highlighting the influence of co-molecules and the application of physical, chemical, and mechanical treatments on their properties. View this paper
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Articles (18)

  • Article
  • Open Access
1,348 Views
12 Pages

9 December 2025

Poly(hydroxyalkanoates) (PHAs) have garnered significant attention due to their biodegradable and biocompatible properties, making them promising alternatives to conventional petroleum-based plastics. As microbial-derived polyesters, PHAs offer a sus...

  • Article
  • Open Access
1 Citations
1,497 Views
16 Pages

8 December 2025

Fused Filament Fabrication (FFF) is an additive manufacturing technique that constructs parts by extruding material layer by layer. It offers advantages such as rapid prototyping, cost-effectiveness, and the ability to produce complex geometries. Thi...

  • Article
  • Open Access
1 Citations
1,458 Views
19 Pages

Antioxidant, Photoprotective, and In Vitro Antiaging Assessment of Optimized Water/Oil Emulsions of Selenized Chickpea Glutelin with Rosehip Oil or Grapeseed Oil

  • Ada Keila Milán-Noris,
  • Ángel R. Rábago-Monzón,
  • Maritza G. Castro-Quintero,
  • Marilena Antunes-Ricardo,
  • Álvaro Montoya-Rodríguez,
  • Julio Montes-Ávila,
  • Cuauhtémoc Reyes-Moreno and
  • Daniela Guardado-Félix

4 December 2025

The selenized glutelin (Se-G) from Se-enriched chickpea sprouts has demonstrated high antioxidant potential. In this study, the response surface methodology was employed to optimize Se-G content (1–4%) and grape or rosehip oils (10–40%) f...

  • Review
  • Open Access
13 Citations
5,055 Views
24 Pages

From Nature to Science: A Review of the Applications of Pectin-Based Hydrogels

  • Karla Nohemi Rubio-Martin del Campo,
  • María Fernanda Rivas-Gastelum,
  • Luis Eduardo Garcia-Amezquita,
  • Maricruz Sepulveda-Villegas,
  • Edgar R. López-Mena,
  • Jorge L. Mejía-Méndez and
  • Angélica Lizeth Sánchez-López

2 December 2025

Pectin is widely used in different areas like biomedical, pharmaceutical, food, and environmental industries thanks to its gelling properties. Pectin hydrogels are of great interest because of their wide biomedical applications in drug delivery, tiss...

  • Article
  • Open Access
5 Citations
1,955 Views
11 Pages

27 November 2025

Biocompatible electroactive hydrogels with bidirectional pH-responsive bending are important for the creation of biomedical actuators. This study developed chitosan/carboxymethylcellulose (CS/CMC) semi-interpenetrating networks (SIPNs) with different...

  • Review
  • Open Access
2,008 Views
21 Pages

13 November 2025

Ribonucleic acid (RNA) polymerases are macromolecular machines that catalyze the synthesis of RNA macromolecules, the sequences of which are coded for by the sequences of regions of deoxyribonucleic acid (DNA) macromolecules in the nucleus of eukaryo...

  • Review
  • Open Access
17 Citations
6,968 Views
34 Pages

11 November 2025

Owing to their tunable and biocompatible characteristics, collagen- and gelatin-based hydrogels have gained attention in numerous applications, including biomedical, food, pharmaceutical, and environmental. The gelation mechanisms and resulting netwo...

  • Article
  • Open Access
1,832 Views
24 Pages

Liposomal Formulations of L-Asparaginase Conjugated with Cationic Polymers for Enhanced Internalization into Cancer Cells

  • Igor D. Zlotnikov,
  • Alexander A. Ezhov,
  • Alexander V. Borisov,
  • Andrey V. Lukyanov,
  • Denis A. Babkov and
  • Elena V. Kudryashova

7 November 2025

L-asparaginase (L-ASNase) is a vital enzymatic drug widely used for treating acute lymphoblastic leukemia (ALL) and certain lymphomas. However, its clinical application is often limited by a short plasma half-life, pronounced immunogenicity, and syst...

(This article belongs to the Topic Recent Advances in Composite Biomaterials)
  • Article
  • Open Access
5,049 Views
17 Pages

Development of Biodegradable Cups from Corn and Fruit Processing Waste and Its Characterization: A Sustainable Approach

  • Sangram S. Wandhekar,
  • Rajesh B. Kshirsagar,
  • Surendra K. Sadawarte,
  • Rinkesh A. Gosavi,
  • Vaszko Gabor,
  • Ayaz Mukarram Shaikh and
  • Kovács Bela

4 November 2025

Single-use plastic cups and packaging materials pose severe environmental challenges due to their persistent nature and harmful impact on ecosystems and wildlife. Simultaneously, the indiscriminate disposal and burning of agricultural and food proces...

  • Review
  • Open Access
1 Citations
3,773 Views
39 Pages

3 November 2025

Human adenovirus infections are typically self-limiting but can become life-threatening in pediatric populations and immunocompromised individuals. Despite this clinical importance, efforts to develop antiviral drugs against adenoviruses remain limit...

  • Article
  • Open Access
1 Citations
1,938 Views
16 Pages

17 October 2025

Tomato pomace (TP) is a waste product from tomato processing. This study explored its use as a food ingredient by creating an encapsulated TP extract (ETPE). TP was extracted with ethanol using a microwave-assisted method prior to encapsulating with...

  • Article
  • Open Access
1 Citations
2,541 Views
28 Pages

Chitosan-Coated Nanostructured Lipid Carriers (NLCs) Incorporating Esters of Ferulic Acid with Photoprotective Activity

  • Ioanna Pitterou,
  • Ioanna Kostopoulou,
  • Maria-Anna Karadendrou,
  • Marianna Fanouria Mitsioni,
  • Christina Fountzoula,
  • Anastasios Kriebardis,
  • Marianthi Miliaronikolaki,
  • Nikolaos Paraskevopoulos,
  • Andromachi Tzani and
  • Anastasia Detsi

16 October 2025

UV radiation is responsible for acute and chronic adverse effects on the skin. In recent years, it has been shown that various phenolic acids, particularly cinnamic acid derivatives, prevent some of these effects. In the present study, the design and...

(This article belongs to the Special Issue Recent Trends in Carbohydrate-Based Therapeutics)
  • Article
  • Open Access
6 Citations
2,649 Views
18 Pages

Supramolecular Structure and Complexation of Gum Arabic in Aqueous Solutions: What Determines Its Protective Functions in Nature and Technologies?

  • Olga S. Zueva,
  • Mariya A. Klimovitskaya,
  • Polina V. Skvortsova,
  • Tahar Khair,
  • Daria A. Kazantseva,
  • Yuliya Abakumova and
  • Naira R. Gromova

16 October 2025

In this work, the associative behavior of Gum Arabic in aqueous solutions was investigated through dynamic light scattering, nuclear magnetic resonance, and transmission and scanning electron microscopy. It was shown that in small associates, the sph...

  • Review
  • Open Access
3 Citations
2,432 Views
17 Pages

Polyglycerol Systems in Additive Manufacturing: Structure, Properties, and Processing

  • Julie Pearl M. Andal,
  • Roxanne R. Navarro and
  • Reymark D. Maalihan

15 October 2025

Additive manufacturing (AM) demands materials that combine precise printability with reliable thermal and mechanical performance. Polyglycerol (PG)-based macromolecular systems offer exceptional tunability through controlled architecture and chemical...

  • Review
  • Open Access
5 Citations
6,364 Views
80 Pages

State of the Art and Recent Advances on Ester and Ether Derivatives of Polysaccharides from Lignocellulose: Production and Technological Applications

  • Heloise O. M. A. Moura,
  • Aisha V. S. Pereira,
  • Elaine C. de Souza,
  • Adriano M. N. Freitas,
  • Daniella N. R. do Nascimento,
  • Carlos A. C. Kramer,
  • Janaína S. Matos,
  • Jordanna L. B. Costa,
  • Daniel Q. Nobre and
  • Luciene S. de Carvalho
  • + 2 authors

14 October 2025

In an era defined by the imperative for sustainable, high-performance materials, this review examines the development and utility of key ester and ether derivatives from both cellulose and hemicellulose sourced from lignocellulosic biomass, with a sp...

(This article belongs to the Special Issue Advances in Starch and Lignocellulosic-Based Materials)
  • Article
  • Open Access
2 Citations
2,939 Views
13 Pages

2 October 2025

The present study focuses on the extraction, characterisation, and functional properties of pectin-like polymers from tomatoes. The results revealed that the highest pectin yield (35.5%) of the dry weight was extracted at pH 1, whilst the lowest yiel...

  • Review
  • Open Access
15 Citations
11,990 Views
26 Pages

30 September 2025

The most significant barrier against biopolymers’ commercialization is their sensitivity to external factors and poor material properties. In recent years, significant progress has been made to enhance these materials so that they are able to p...

  • Article
  • Open Access
1 Citations
1,177 Views
12 Pages

Evaluation of the Antifungal Activity of Microgramma vacciniifolia Frond Lectin (MvFL) Against Pathogenic Yeasts

  • Rayanne Maria Vitória Vasconcelos de Oliveira,
  • Alexsander Rodrigues Carvalho Junior,
  • Pollyanna Michelle da Silva,
  • Gustavo Ramos Salles Ferreira,
  • Poliana Karla Amorim,
  • Patrícia Maria Guedes Paiva,
  • Luís Cláudio Nascimento da Silva,
  • Leydianne Leite de Siqueira Patriota,
  • Emmanuel Viana Pontual and
  • Thiago Henrique Napoleão

23 September 2025

The rise in antifungal resistance among Candida species has prompted the search for alternative therapies, including plant-derived lectins with antimicrobial properties. This study evaluated the antifungal activity of Microgramma vacciniola frond lec...

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Macromol - ISSN 2673-6209