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Volume 6
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Review

Food Safety Promotion via Nanotechnology: An Argumentative Review on Nano-Sanitizers

by
Lok R. Pokhrel
1,*,
Caroline A. Knowles
1,2 and
Pradnya T. Akula
1,3
1
Department of Public Health, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
2
Centricity Research, Morehead City, NC 28557, USA
3
Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC 28262, USA
*
Author to whom correspondence should be addressed.
Appl. Nano 2025, 6(4), 21; https://doi.org/10.3390/applnano6040021
Submission received: 14 July 2025 / Revised: 3 September 2025 / Accepted: 5 September 2025 / Published: 1 October 2025
(This article belongs to the Topic Nano-Enabled Innovations in Agriculture)
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Abstract

Nano-sanitizers, which exploit the unique physicochemical properties of nanomaterials, are being increasingly investigated as innovative tools to promote food safety. In this argumentative review, we compare and contrast nano-sanitizers with conventional sanitation methods by examining their underlying antimicrobial mechanisms, multifaceted benefits, inherent challenges, and wide-ranging public health implications. We evaluate regulatory conundrums and consumer perspectives alongside future outlooks for integration with advanced technologies such as artificial intelligence. Through selective synthesis of the published literature, our argumentative discussion demonstrates that nano-sanitizers not only promise superior performance in pathogen inactivation but could also contribute to overall food system sustainability, provided safety and regulatory concerns are adequately addressed.
Keywords: nanomaterials; surface decontamination; antimicrobials; food pathogens; regulations; public health nanomaterials; surface decontamination; antimicrobials; food pathogens; regulations; public health

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MDPI and ACS Style

Pokhrel, L.R.; Knowles, C.A.; Akula, P.T. Food Safety Promotion via Nanotechnology: An Argumentative Review on Nano-Sanitizers. Appl. Nano 2025, 6, 21. https://doi.org/10.3390/applnano6040021

AMA Style

Pokhrel LR, Knowles CA, Akula PT. Food Safety Promotion via Nanotechnology: An Argumentative Review on Nano-Sanitizers. Applied Nano. 2025; 6(4):21. https://doi.org/10.3390/applnano6040021

Chicago/Turabian Style

Pokhrel, Lok R., Caroline A. Knowles, and Pradnya T. Akula. 2025. "Food Safety Promotion via Nanotechnology: An Argumentative Review on Nano-Sanitizers" Applied Nano 6, no. 4: 21. https://doi.org/10.3390/applnano6040021

APA Style

Pokhrel, L. R., Knowles, C. A., & Akula, P. T. (2025). Food Safety Promotion via Nanotechnology: An Argumentative Review on Nano-Sanitizers. Applied Nano, 6(4), 21. https://doi.org/10.3390/applnano6040021

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