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Review

Benzo[1,2,3]dithiazole Compounds: A History of Synthesis and Their Renewed Applicability in Materials and Synthetic Chemistry, Originating from the Herz Reaction

Department of Chemistry, University of Durham, South Road, Durham DH1 3LE, UK
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Author to whom correspondence should be addressed.
Academic Editors: Silvana Pedatella and Dmitry Yu. Murzin
Reactions 2021, 2(3), 175-208; https://doi.org/10.3390/reactions2030013
Received: 3 May 2021 / Revised: 18 June 2021 / Accepted: 24 June 2021 / Published: 29 June 2021
(This article belongs to the Special Issue Feature Papers in Reactions in 2021)
The benzo[1,2,3]dithiazole is a unique heteroaromatic functionality whose conjugated profile instils some fascinating electronic properties. This has been historically recognized in the design and manufacture of organic dyes early last century. Although, with the benefit of increased diagnostic techniques and improved understanding, these structures are attracting greater attention in additional research settings, including applications as organic radicals and semiconductors. In addition, the benzodithiazole functionality has been shown to be a valuable synthetic intermediate in the preparation of a variety of other privileged aromatic and heteroaromatic targets, many of which are important APIs. In this review, the authors aim to critically analyse the potential applicability of these compounds to the fields of not only small-scale laboratory synthetic and medicinal chemistry but also commercial-scale processes and increasingly materials chemistry. View Full-Text
Keywords: thiazole; disulfur dichloride; Herz reaction; heterocycle formation; organic radical anion; semiconductor; dye thiazole; disulfur dichloride; Herz reaction; heterocycle formation; organic radical anion; semiconductor; dye
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MDPI and ACS Style

Nicholls, A.J.; Baxendale, I.R. Benzo[1,2,3]dithiazole Compounds: A History of Synthesis and Their Renewed Applicability in Materials and Synthetic Chemistry, Originating from the Herz Reaction. Reactions 2021, 2, 175-208. https://doi.org/10.3390/reactions2030013

AMA Style

Nicholls AJ, Baxendale IR. Benzo[1,2,3]dithiazole Compounds: A History of Synthesis and Their Renewed Applicability in Materials and Synthetic Chemistry, Originating from the Herz Reaction. Reactions. 2021; 2(3):175-208. https://doi.org/10.3390/reactions2030013

Chicago/Turabian Style

Nicholls, Alexander J., and Ian R. Baxendale 2021. "Benzo[1,2,3]dithiazole Compounds: A History of Synthesis and Their Renewed Applicability in Materials and Synthetic Chemistry, Originating from the Herz Reaction" Reactions 2, no. 3: 175-208. https://doi.org/10.3390/reactions2030013

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