High-Throughput, Volume 8, Issue 2 (June 2019) – 10 articles
Cover Story (view full-size image): The mass spectrometric measurement of DNA adducts, the covalent modifications of DNA by environmental and dietary genotoxicants,and endogenously produced electrophiles, provides physico-chemical evidence for DNA damage. As the mass spectrometry-based analytical technology matures and bioinformatics tools become available for large data analysis, it will be feasible to screen for the totality of DNA damage in the human genome through DNA adductomics approaches. As an emerging technology in human exposure assessment, DNA adductomics can advance our understanding about the role of chemical exposures in DNA damage and disease risk. View this paper.
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