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Advances in Respiratory Medicine, Volume 93, Issue 5

2025 October - 16 articles

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Articles (16)

  • Review
  • Open Access
2 Citations
1,854 Views
40 Pages

Leveraging Artificial Intelligence for the Diagnosis of Systemic Sclerosis Associated Pulmonary Arterial Hypertension: Opportunities, Challenges, and Future Perspectives

  • Samiksha Jain,
  • Avneet Kaur,
  • Abdul Qadeer,
  • Victor Ghosh,
  • Shivani Thota,
  • Mallareddy Banala,
  • Jieun Lee,
  • Gayathri Yerrapragada,
  • Poonguzhali Elangovan and
  • Shivaram P. Arunachalam
  • + 11 authors

Systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) is a life-threatening vascular complication of SSc, marked by high morbidity and mortality. Early diagnosis remains a major challenge due to nonspecific symptoms and the limitati...

  • Article
  • Open Access
1,916 Views
15 Pages

Beyond the Apnea–Hypopnea Index: Exploring Time-Dependent Hazard Ratios of Respiratory Events in Obstructive Sleep Apnea

  • Wojciech Kuczyński,
  • Aleksandra Kudrycka,
  • Karol Pierzchała,
  • Izabela Grabska-Kobyłecka,
  • Michael Pencina,
  • Sebastian Sakowski and
  • Piotr Białasiewicz

Obstructive sleep apnea (OSA) is associated with increased risks of systemic comorbidities, leading to significant morbidity and mortality. This study investigates predictors of all-cause mortality, emphasizing the interplay of clinical symptoms, pol...

  • Article
  • Open Access
2,348 Views
13 Pages

Pressurized Metered-Dose Inhaler Versus Dry Powder Inhaler Adherence Among Individuals with Asthma and COPD

  • Dekel Shlomi,
  • Bernice Oberman,
  • Yehonatan Halevy,
  • Shiri Kushnir,
  • Hadas Meir and
  • Yael Reichenberg

Background: The core management of most individuals with asthma and COPD is daily treatment with inhalers such as inhaled corticosteroids (ICS) and long-acting bronchodilators. The two main types of inhalers used are pressurized metered-dose inhalers...

  • Article
  • Open Access
1 Citations
1,040 Views
19 Pages

The Effort, Dyspnea, and Cooperation Scores in Mild and Moderate Post-COVID-19 Patients: Results of a Retrospective Study

  • Ovidiu Cristian Chiriac,
  • Corina Sporea,
  • Daniela Miricescu,
  • Ana Raluca Mitrea,
  • Ileana Adela Vacaroiu,
  • Raluca Grigore and
  • Adriana Sarah Nica

COVID-19 signs and symptoms varied among patients, with the most common being fever, fatigue, sore throat, cough, anorexia, and shortness of breath. (1) Background: This study aimed to assess effort, dyspnea, and cooperation scores in patients with m...

  • Article
  • Open Access
848 Views
12 Pages

Background and Objectives: Hematological parameters are increasingly being investigated as readily accessible biomarkers for the diagnosis of obstructive sleep apnea syndrome (OSAS). In our study, we aimed to investigate the relationship between OSAS...

  • Article
  • Open Access
961 Views
11 Pages

Development of a Tool to Assess the Severity of Pulmonary Hypertension in Patients with Interstitial Lung Disease: A Guide to Assist Therapeutic Choices

  • Garrett Fiscus,
  • Chebly Dagher,
  • David O’Sullivan,
  • Brett Carollo,
  • Kristen Swanson,
  • Harrison W. Farber and
  • Raj Parikh

Background: Pulmonary hypertension (PH) is a frequent complication in patients with interstitial lung disease (ILD); its occurrence results in significant morbidity and mortality. Currently approved treatment options for PH-ILD include inhaled prosta...

  • Article
  • Open Access
1,516 Views
13 Pages

Real-World Efficacy of Beclomethasone Dipropionate/Formoterol Fumarate/Glycopyrronium on Diaphragmatic Workload Assessed by Ultrasound and Lung Function in Patients with Uncontrolled Asthma

  • Antonio Maiorano,
  • Anna Ferrante Bannera,
  • Chiara Lupia,
  • Daniela Pastore,
  • Emanuela Chiarella,
  • Giovanna Lucia Piazzetta,
  • Angelantonio Maglio,
  • Alessandro Vatrella,
  • Girolamo Pelaia and
  • Corrado Pelaia

Background: Uncontrolled asthma remains a significant clinical challenge, often linked to impaired lung function and increased diaphragmatic workload. Recent studies have shown promising results using a triple inhaled therapy comprising beclomethason...

  • Article
  • Open Access
1,572 Views
23 Pages

NSCLC EGFR Mutation Prediction via Random Forest Model: A Clinical–CT–Radiomics Integration Approach

  • Anass Benfares,
  • Badreddine Alami,
  • Sara Boukansa,
  • Mamoun Qjidaa,
  • Ikram Benomar,
  • Mounia Serraj,
  • Ahmed Lakhssassi,
  • Mohammed Ouazzani Jamil,
  • Mustapha Maaroufi and
  • Hassan Qjidaa

26 September 2025

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide. Accurate determination of epidermal growth factor receptor (EGFR) mutation status is essential for selecting patients eligible for tyrosine kinase inhibito...

  • Review
  • Open Access
1,233 Views
24 Pages

26 September 2025

Respiratory infections and chronic lung disease are major contributors to morbidity in children. Aztreonam lysine for inhalation (AZLI) delivers high local antibiotic concentrations while limiting systemic exposure; however, its safety in younger pat...

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Adv. Respir. Med. - ISSN 2543-6031