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Article

Fabrication and Characterization of Polylactic Acid Electrospun Scaffolds Modified with Multi-Walled Carbon Nanotubes and Hydroxyapatite Nanoparticles

1
Department of Mechanical Engineering and Aeronautics, Patras University Campus, University of Patras, GR-26504 Patras, Greece
2
Foundation of Research and Technology, Institute of Chemical Engineering Sciences (FORTH/ICE-HT), GR-26504 Patras, Greece
*
Author to whom correspondence should be addressed.
Biomimetics 2020, 5(3), 43; https://doi.org/10.3390/biomimetics5030043
Received: 15 August 2020 / Revised: 20 August 2020 / Accepted: 20 August 2020 / Published: 2 September 2020
The solution electrospinning process (SEP) is a cost-effective technique in which a wide range of polymeric materials can be electrospun. Electrospun materials can also be easily modified during the solution preparation process (prior SEP). Based on this, the aim of the current work is the fabrication and nanomodification of scaffolds using SEP, and the investigation of their porosity and physical and mechanical properties. In this study, polylactic acid (PLA) was selected for scaffold fabrication, and further modified with multi-walled carbon nanotubes (MWCNTs) and hydroxyapatite (HAP) nanoparticles. After fabrication, porosity calculation and physical and mechanical characterization for all scaffold types were conducted. More precisely, the morphology of the fibers (in terms of fiber diameter), the surface properties (in terms of contact angle) and the mechanical properties under the tensile mode of the fabricated scaffolds have been investigated and further compared against pristine PLA scaffolds (without nanofillers). Finally, the scaffold with the optimal properties was proposed as the candidate material for potential future cell culturing. View Full-Text
Keywords: polylactic acid; electrospinning; scaffolds; contact angle; porosity; mechanical properties; MWCNTs; hydroxyapatite polylactic acid; electrospinning; scaffolds; contact angle; porosity; mechanical properties; MWCNTs; hydroxyapatite
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MDPI and ACS Style

Kotrotsos, A.; Yiallouros, P.; Kostopoulos, V. Fabrication and Characterization of Polylactic Acid Electrospun Scaffolds Modified with Multi-Walled Carbon Nanotubes and Hydroxyapatite Nanoparticles. Biomimetics 2020, 5, 43. https://doi.org/10.3390/biomimetics5030043

AMA Style

Kotrotsos A, Yiallouros P, Kostopoulos V. Fabrication and Characterization of Polylactic Acid Electrospun Scaffolds Modified with Multi-Walled Carbon Nanotubes and Hydroxyapatite Nanoparticles. Biomimetics. 2020; 5(3):43. https://doi.org/10.3390/biomimetics5030043

Chicago/Turabian Style

Kotrotsos, Athanasios, Prokopis Yiallouros, and Vassilis Kostopoulos. 2020. "Fabrication and Characterization of Polylactic Acid Electrospun Scaffolds Modified with Multi-Walled Carbon Nanotubes and Hydroxyapatite Nanoparticles" Biomimetics 5, no. 3: 43. https://doi.org/10.3390/biomimetics5030043

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