Supramolecular Tripeptide Hydrogel Assembly with 5-Fluorouracil
AbstractIn this work, we present Thioflavin T fluorescence, transmission electron microscopy (TEM), circular dichroism (CD), Fourier-transformed infrared (FT-IR), and oscillatory rheometry studies applied to an antineoplastic drug, 5-fluorouracil (5-FU), embedded in a heterochiral tripeptide hydrogel to obtain a drug delivery supramolecular system. The release of 5-fluorouracil was monitored over time by reverse-phase high-performance liquid chromatography (HPLC) and its interaction with the tripeptide assemblies was probed by all-atom molecular dynamics simulations. View Full-Text
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Parisi, E.; Garcia, A.M.; Marson, D.; Posocco, P.; Marchesan, S. Supramolecular Tripeptide Hydrogel Assembly with 5-Fluorouracil. Gels 2019, 5, 5.
Parisi E, Garcia AM, Marson D, Posocco P, Marchesan S. Supramolecular Tripeptide Hydrogel Assembly with 5-Fluorouracil. Gels. 2019; 5(1):5.Chicago/Turabian Style
Parisi, Evelina; Garcia, Ana M.; Marson, Domenico; Posocco, Paola; Marchesan, Silvia. 2019. "Supramolecular Tripeptide Hydrogel Assembly with 5-Fluorouracil." Gels 5, no. 1: 5.
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