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6,375 Results Found

  • Article
  • Open Access
3 Citations
2,480 Views
12 Pages

Self-Assembly at a Macroscale Using Aerodynamics

  • Yi Liu,
  • Yuting Chen,
  • Xiaowu Jiang,
  • Qianying Ni,
  • Chen Liu,
  • Fangfang Shang,
  • Qingchao Xia and
  • Sheng Zhang

30 July 2022

Intuitive self-assembly devices are of great significance to the emerging applications of self-assembly theory. In this paper, a novel intuitive device with an aerodynamic system is fabricated for the self-assembly experiment. Table tennis balls were...

  • Review
  • Open Access
15 Citations
5,260 Views
24 Pages

Stimuli-Responsive Macromolecular Self-Assembly

  • Chunqiang Jiang,
  • Guohe Xu and
  • Jianping Gao

19 September 2022

Macromolecular self-assembly has great potential for application in the field of the design of molecular machines, in molecular regulation, for biological tissue, and in biomedicine for the optical, electrical, and biological characteristics that the...

  • Feature Paper
  • Article
  • Open Access
8 Citations
5,146 Views
33 Pages

Self-Assembly and Self-Repair during Motion with Modular Robots

  • Robert H. Peck,
  • Jon Timmis and
  • Andy M. Tyrrell

Self-reconfigurable modular robots consist of multiple modular elements and have the potential to enable future autonomous systems to adapt themselves to handle unstructured environments, novel tasks, or damage to their constituent elements. This pap...

  • Review
  • Open Access
29 Citations
8,514 Views
36 Pages

27 August 2020

Recently, the design of novel supramolecular chiral materials has received a great deal of attention due to rapid developments in the fields of supramolecular chemistry and molecular self-assembly. Supramolecular chirality has been widely introduced...

  • Review
  • Open Access
30 Citations
8,554 Views
15 Pages

Role of Entropy in Colloidal Self-Assembly

  • Brunno C. Rocha,
  • Sanjib Paul and
  • Harish Vashisth

10 August 2020

Entropy plays a key role in the self-assembly of colloidal particles. Specifically, in the case of hard particles, which do not interact or overlap with each other during the process of self-assembly, the free energy is minimized due to an increase i...

  • Review
  • Open Access
72 Citations
16,883 Views
21 Pages

Self-Assembly: From Amphiphiles to Chromophores and Beyond

  • Jonathan P. Hill,
  • Lok Kumar Shrestha,
  • Shinsuke Ishihara,
  • Qingmin Ji and
  • Katsuhiko Ariga

23 June 2014

Self-assembly has been recognised as a ubiquitous aspect of modern chemistry. Our understanding and applications of self-assembly are substantially based on what has been learned from biochemical systems. In this review, we describe various aspects o...

  • Review
  • Open Access
20 Citations
10,756 Views
24 Pages

Chemical Reactions Directed Peptide Self-Assembly

  • Dnyaneshwar B. Rasale and
  • Apurba K. Das

13 May 2015

Fabrication of self-assembled nanostructures is one of the important aspects in nanoscience and nanotechnology. The study of self-assembled soft materials remains an area of interest due to their potential applications in biomedicine. The versatile p...

  • Review
  • Open Access
19 Citations
14,825 Views
17 Pages

Self-Assembly of Optical Molecules with Supramolecular Concepts

  • Ken Okamoto,
  • Parayalil Chithra,
  • Gary J. Richards,
  • Jonathan P. Hill and
  • Katsuhiko Ariga

27 April 2009

Fabrication of nano-sized objects is one of the most important issues in nanoscience and nanotechnology. Soft nanomaterials with flexible properties have been given much attention and can be obtained through bottom-up processing from functional molec...

  • Feature Paper
  • Review
  • Open Access
2 Citations
3,912 Views
19 Pages

Self-Assembly in Curved Space: Ordering, Defect and Entropy

  • Yuming Wang,
  • Haixiao Wan,
  • Lijuan Gao,
  • Yibo Wu and
  • Li-Tang Yan

2 January 2024

Self-assembly of nanoscale objects is of essential importance in materials science, condensed matter physics, and biophysics. Curvature modifies the principles and sequence of self-assembly in Euclidean space, resulting in unique and more complex str...

  • Article
  • Open Access
9 Citations
4,317 Views
14 Pages

14 August 2019

Fluorescence titration of methylene blue, rhodamine B and rhodamine 6G (R6G) by silver nanoparticle (AgNP) all resulted in an initial steep quenching curve followed with a sharp turn and a much flatter quenching curve. At the turn, there are about 20...

  • Review
  • Open Access
32 Citations
8,426 Views
14 Pages

Bottom-Up Self-Assembly Based on DNA Nanotechnology

  • Xuehui Yan,
  • Shujing Huang,
  • Yong Wang,
  • Yuanyuan Tang and
  • Ye Tian

16 October 2020

Manipulating materials at the atomic scale is one of the goals of the development of chemistry and materials science, as it provides the possibility to customize material properties; however, it still remains a huge challenge. Using DNA self-assembly...

  • Review
  • Open Access
18 Citations
6,536 Views
25 Pages

Development of Self-Assembly Methods on Quantum Dots

  • Qun Hao,
  • Hongyu Lv,
  • Haifei Ma,
  • Xin Tang and
  • Menglu Chen

3 February 2023

Quantum dot materials, with their unique photophysical properties, are promising zero-dimensional materials for encryption, display, solar cells, and biomedical applications. However, due to the large surface to volume ratio, they face the challenge...

  • Review
  • Open Access
113 Citations
15,947 Views
18 Pages

S-Layer Protein Self-Assembly

  • Dietmar Pum,
  • Jose Luis Toca-Herrera and
  • Uwe B. Sleytr

25 January 2013

Crystalline S(urface)-layers are the most commonly observed cell surface structures in prokaryotic organisms (bacteria and archaea). S-layers are highly porous protein meshworks with unit cell sizes in the range of 3 to 30 nm, and thicknesses of ~10...

  • Article
  • Open Access
7 Citations
8,305 Views
13 Pages

Multivalent Protein Assembly Using Monovalent Self-Assembling Building Blocks

  • Katja Petkau-Milroy,
  • Michael H. Sonntag,
  • Alexander Colditz and
  • Luc Brunsveld

22 October 2013

Discotic molecules, which self-assemble in water into columnar supramolecular polymers, emerged as an alternative platform for the organization of proteins. Here, a monovalent discotic decorated with one single biotin was synthesized to study the se...

  • Article
  • Open Access
21 Citations
10,365 Views
24 Pages

The Influence of Shape on Parallel Self-Assembly

  • Shuhei Miyashita,
  • Zoltán Nagy,
  • Bradley J. Nelson and
  • Rolf Pfeifer

23 October 2009

Self-assembly is a key phenomenon whereby vast numbers of individual components passively interact and form organized structures, as can be seen, for example, in the morphogenesis of a virus. Generally speaking, the process can be viewed as a spatial...

  • Article
  • Open Access
4 Citations
2,517 Views
13 Pages

Influence of Electrostatic Interactions on the Self-Assembly of Charged Peptides

  • Xue Sun,
  • Bolan Wu,
  • Na Li,
  • Bo Liu,
  • Shijun Li,
  • Liang Ma and
  • Hangyu Zhang

20 January 2025

Peptides can be designed to self-assemble into predefined supramolecular nanostructures, which are then employed as biomaterials in a range of applications, including tissue engineering, drug delivery, and vaccination. However, current self-assemblin...

  • Review
  • Open Access
41 Citations
11,410 Views
21 Pages

Self-Assembly in Biosilicification and Biotemplated Silica Materials

  • Francisco M. Fernandes,
  • Thibaud Coradin and
  • Carole Aimé

4 September 2014

During evolution, living organisms have learned to design biomolecules exhibiting self-assembly properties to build-up materials with complex organizations. This is particularly evidenced by the delicate siliceous structures of diatoms and sponges. T...

  • Feature Paper
  • Review
  • Open Access
25 Citations
10,025 Views
27 Pages

Gels Obtained by Colloidal Self-Assembly of Amphiphilic Molecules

  • Paula Malo de Molina and
  • Michael Gradzielski

3 August 2017

Gelation in water-based systems can be achieved in many different ways. This review focusses on ways that are based on self-assembly, i.e., a bottom-up approach. Self-assembly naturally requires amphiphilic molecules and accordingly the systems descr...

  • Review
  • Open Access
124 Citations
16,290 Views
16 Pages

22 August 2011

Protein self-assembly, through specific, high affinity, and geometrically constraining protein-protein interactions, can control and lead to complex cellular nano-structures. Establishing an understanding of the underlying principles that govern prot...

  • Review
  • Open Access
61 Citations
6,920 Views
18 Pages

Self-Assembly of Metal Nanoclusters for Aggregation-Induced Emission

  • Jianxing Wang,
  • Xiangfang Lin,
  • Tong Shu,
  • Lei Su,
  • Feng Liang and
  • Xueji Zhang

Aggregation-induced emission (AIE) is an intriguing strategy to enhance the luminescence of metal nanoclusters (NCs). However, the morphologies of aggregated NCs are often irregular and inhomogeneous, leading to instability and poor color purity of t...

  • Article
  • Open Access
2 Citations
6,251 Views
14 Pages

Self-Assembly of Human Serum Albumin: A Simplex Phenomenon

  • Garima Thakur,
  • Kovur Prashanthi,
  • Keren Jiang and
  • Thomas Thundat

20 September 2017

Spontaneous self-assemblies of biomolecules can generate geometrical patterns. Our findings provide an insight into the mechanism of self-assembled ring pattern generation by human serum albumin (HSA). The self-assembly is a process guided by kinetic...

  • Article
  • Open Access
4 Citations
2,344 Views
18 Pages

Self-Assembly of Palmitic Acid in the Presence of Choline Hydroxide

  • Huifang Xu,
  • Xin Liang,
  • Song Lu,
  • Meihua Gao,
  • Sijia Wang and
  • Yuanyuan Li

7 November 2023

To disperse fatty acids in aqueous solution, choline, a quaternary ammonium ion, has been used recently. So far, only the self-assembly of myristic acid (MA) in the presence of choline hydroxide as a function of the molar ratio has been investigated,...

  • Review
  • Open Access
14 Citations
4,201 Views
20 Pages

Pillararenes Trimer for Self-Assembly

  • Huacheng Zhang,
  • Zhaona Liu and
  • Hui Fu

31 March 2020

Pillararenes trimer with particularly designed structural geometry and excellent capacity of recognizing guest molecules is a very efficient and attractive building block for the fabrication of advanced self-assembled materials. Pillararenes trimers...

  • Review
  • Open Access
21 Citations
9,888 Views
30 Pages

Self-Assembly of Polymers and Their Applications in the Fields of Biomedicine and Materials

  • Lina Hu,
  • Shujing Zhou,
  • Xiumei Zhang,
  • Chengyang Shi,
  • Yifan Zhang and
  • Xiaoyi Chen

23 July 2024

Polymer self-assembly can prepare various shapes and sizes of pores, making it widely used. The complexity and diversity of biomolecules make them a unique class of building blocks for precise assembly. They are particularly suitable for the new gene...

  • Review
  • Open Access
6 Citations
7,123 Views
67 Pages

Modern Trends in Polymerization-Induced Self-Assembly

  • Natalia S. Serkhacheva,
  • Nickolay I. Prokopov,
  • Evgenii A. Lysenko,
  • Elena Yu. Kozhunova and
  • Elena V. Chernikova

15 May 2024

Polymerization-induced self-assembly (PISA) is a powerful and versatile technique for producing colloidal dispersions of block copolymer particles with desired morphologies. Currently, PISA can be carried out in various media, over a wide range of te...

  • Article
  • Open Access
1 Citations
1,484 Views
12 Pages

Nanoscale Spatial Control over the Self-Assembly of Small Molecule Hydrogelators

  • Samahir Sheikh Idris,
  • Hucheng Wang,
  • Yuliang Gao,
  • Peiwen Cai,
  • Yiming Wang and
  • Shicheng Zhao

14 April 2025

Spatial control over molecular self-assembly at the nano scale offers great potential for many high-tech applications, yet remains a challenging task. Here, we report a polymer brush-mediated strategy to confine the self-assembly of hydrazone-based h...

  • Review
  • Open Access
56 Citations
8,092 Views
28 Pages

Protein Supramolecular Structures: From Self-Assembly to Nanovaccine Design

  • Ximena Zottig,
  • Mélanie Côté-Cyr,
  • Dominic Arpin,
  • Denis Archambault and
  • Steve Bourgault

Life-inspired protein supramolecular assemblies have recently attracted considerable attention for the development of next-generation vaccines to fight against infectious diseases, as well as autoimmune diseases and cancer. Protein self-assembly enab...

  • Review
  • Open Access
20 Citations
5,502 Views
17 Pages

Recent Advances in Self-Assembly and Application of Para-Aramids

  • Chunjie Xie,
  • Shixuan Yang,
  • Ran He,
  • Jianning Liu,
  • Yuexi Chen,
  • Yongyi Guo,
  • Zhaoxia Guo,
  • Teng Qiu and
  • Xinlin Tuo

Poly(p-phenylene terephthalamide) (PPTA) is one kind of lyotropic liquid crystal polymer. Kevlar fibers performed from PPTA are widely used in many fields due to their superior mechanical properties resulting from their highly oriented macromolecular...

  • Article
  • Open Access
8 Citations
4,637 Views
24 Pages

Self-Assembly, Self-Folding, and Origami: Comparative Design Principles

  • John R. Jungck,
  • Stephen Brittain,
  • Donald Plante and
  • James Flynn

Self-assembly is usually considered a parallel process while self-folding and origami are usually considered to be serial processes. We believe that these distinctions do not hold in actual experiments. Based upon our experience with 4D printing, we...

  • Article
  • Open Access
8 Citations
3,230 Views
13 Pages

Self-Assembly of Rhein and Matrine Nanoparticles for Enhanced Wound Healing

  • Xunxun Wu,
  • Ranqing Zang,
  • Yiting Qiu,
  • Ni Yang,
  • Meiyan Liu,
  • Site Wei,
  • Xianxiang Xu and
  • Yong Diao

15 July 2024

Carrier-free self-assembly has gradually shifted the focus of research on natural products, which effectively improve the bioavailability and the drug-loading rate. However, in spite of the existing studies, the development of self-assembled natural...

  • Article
  • Open Access
10 Citations
2,780 Views
10 Pages

Roles of Self-Assembly and Secondary Structures in Antimicrobial Peptide Coatings

  • Xiao Zhu,
  • Weilong Tang,
  • Xinyi Cheng,
  • Huihui Wang,
  • Ting Sang and
  • Zhou Ye

2 October 2022

Antimicrobial peptide (AMP) coatings are promising alternatives to conventional antibiotics for the prevention of medical device- and implant-associated infections. Compared to covalent immobilization methods, coatings relying on physical interaction...

  • Review
  • Open Access
19 Citations
9,153 Views
20 Pages

Synthesis and Self-Assembly of Conjugated Block Copolymers

  • Lin-Lin Xiao,
  • Xu Zhou,
  • Kan Yue and
  • Zi-Hao Guo

29 December 2020

In the past two decades, conjugated polymers (CPs) have drawn great attention due to their excellent conductivity and charge mobility, rendering them broad applications in organic electronics. Controlling over the morphologies and nanostructures of C...

  • Review
  • Open Access
86 Citations
19,429 Views
25 Pages

Polymers Comprising Cholesterol: Synthesis, Self-Assembly, and Applications

  • Yuxiang Zhou,
  • Victoria A. Briand,
  • Nitin Sharma,
  • Suk-kyun Ahn and
  • Rajeswari M. Kasi

2 June 2009

This article reviews the current status of self-assembling liquid crystalline polymers comprising cholesterol. This article will focus on synthesis, structure-property relationships and strategies to direct ordering and packing of meso- and nanostruc...

  • Article
  • Open Access
489 Views
42 Pages

19 December 2025

Starch complexes have recently been identified as a new dietary supplement for dietary intervention in glycemic metabolism disorders. However, although the amylopectin significantly influenced starch complexes’ anti-digestibility, the underlyin...

  • Review
  • Open Access
71 Citations
6,888 Views
20 Pages

Inhibition of the Self-Assembly of Aβ and of Tau by Polyphenols: Mechanistic Studies

  • Qiuchen Zheng,
  • Micheal T. Kebede,
  • Merc M. Kemeh,
  • Saadman Islam,
  • Bethany Lee,
  • Stuart D. Bleck,
  • Liliana A. Wurfl and
  • Noel D. Lazo

22 June 2019

The amyloid-β (Aβ) peptide and tau protein are thought to play key neuropathogenic roles in Alzheimer’s disease (AD). Both Aβ and tau self-assemble to form the two major pathological hallmarks of AD: amyloid plaques and neurofibr...

  • Review
  • Open Access
57 Citations
10,467 Views
69 Pages

18 July 2020

Different classes of foldamers, which are synthetic oligomers that adopt well-defined conformations in solution, have been the subject of extensive studies devoted to the elucidation of the forces driving their secondary structures and their potentia...

  • Article
  • Open Access
1 Citations
952 Views
15 Pages

The Influence of Endogenous Derivatives on the Self-Assembly of Carbonized Polymer Dots

  • Yingxi Qin,
  • Wenkai Zhang,
  • Ziwei Liu,
  • Mingyan Jia,
  • Jie Chi,
  • Yujia Liu,
  • Yue Wang,
  • Aimiao Qin,
  • Yu Wang and
  • Liang Feng

20 March 2025

Carbonized polymer dots (CPDs) have emerged as a fascinating class of functional nanomaterials with unique physicochemical properties. However, the mechanisms governing their formation and photoluminescence remain a subject of intense debate. In this...

  • Article
  • Open Access
3 Citations
2,181 Views
11 Pages

A Spike-like Self-Assembly of Polyaspartamide Integrated with Functionalized Nanoparticles

  • Sa Ra Han,
  • Yujin Ahn,
  • Sungwoo Cho,
  • Hyewon Jeong,
  • Yoonsook Ji,
  • Woonggyu Jung and
  • Jae Hyun Jeong

15 January 2024

The integration of nanoparticles (NPs) into molecular self-assemblies has been extensively studied with the aim of building well-defined, ordered structures which exhibit advanced properties and performances. This study demonstrates a novel strategy...

  • Review
  • Open Access
16 Citations
5,314 Views
18 Pages

Self-Assembly of DNA-Grafted Colloids: A Review of Challenges

  • Manish Dwivedi,
  • Swarn Lata Singh,
  • Atul S. Bharadwaj,
  • Vimal Kishore and
  • Ajay Vikram Singh

14 July 2022

DNA-mediated self-assembly of colloids has emerged as a powerful tool to assemble the materials of prescribed structure and properties. The uniqueness of the approach lies in the sequence-specific, thermo-reversible hybridization of the DNA-strands b...

  • Communication
  • Open Access
6 Citations
3,103 Views
11 Pages

Self-Assembly of Asymmetrically Functionalized Titania Nanoparticles into Nanoshells

  • Fredric G. Svensson,
  • Gulaim A. Seisenbaeva,
  • Nicholas A. Kotov and
  • Vadim G. Kessler

29 October 2020

Titania (anatase) nanoparticles were anisotropically functionalized in water-toluene Pickering emulsions to self-assemble into nanoshells with diameters from 500 nm to 3 μm as candidates for encapsulation of drugs and other compounds. The water-ph...

  • Communication
  • Open Access
7 Citations
4,855 Views
14 Pages

19 September 2018

Intracellular protein delivery is an invaluable tool for biomedical research, as it enables fundamental studies of cellular processes and creates opportunities for novel therapeutic development. Protein delivery reagents such as cell penetration pept...

  • Review
  • Open Access
12 Citations
4,467 Views
18 Pages

25 August 2022

Self-assembled biomaterials have been widely explored for real-time fluorescence imaging, imaging-guided surgery, and targeted therapy for tumors, etc. In particular, small molecule-based self-assembly has been established as a reliable strategy for...

  • Review
  • Open Access
148 Citations
19,500 Views
14 Pages

The Phe-Phe Motif for Peptide Self-Assembly in Nanomedicine

  • Silvia Marchesan,
  • Attilio V. Vargiu and
  • Katie E. Styan

3 November 2015

Since its discovery, the Phe-Phe motif has gained in popularity as a minimalist building block to drive the self-assembly of short peptides and their analogues into nanostructures and hydrogels. Molecules based on the Phe-Phe motif have found a range...

  • Review
  • Open Access
27 Citations
17,381 Views
32 Pages

Self-Assembly in Micro- and Nanofluidic Devices: A Review of Recent Efforts

  • Hwa Seng Khoo,
  • Cheng Lin,
  • Shih-Hao Huang and
  • Fan-Gang Tseng

11 February 2011

Self-assembly in micro- and nanofluidic devices has been the focus of much attention in recent years. This is not only due to their advantages of self-assembling with fine temporal and spatial control in addition to continuous processing that is not...

  • Article
  • Open Access
1 Citations
1,233 Views
14 Pages

Anion-Induced Self-Assembly of Bis(cyclopeptides) with Rigid Linkers

  • Elisavet Kaitatzi,
  • Linda Fritsche and
  • Stefan Kubik

13 August 2025

The presence of sulfate anions induces the self-assembly of anion-binding bis(cyclopeptides) in which two cyclopeptide rings are connected via a rigid linker. In this way, 2:2 complexes are formed in which two anions are sandwiched between two bis(cy...

  • Feature Paper
  • Article
  • Open Access
9 Citations
4,995 Views
17 Pages

3 September 2020

To date, amphiphilic block copolymers (BCPs) containing poly(vinylidene fluoride-co-hexafluoropropene) (P(VDF-co-HFP)) copolymers are rare. At moderate content of HFP, this fluorocopolymer remains semicrystalline and is able to crystallize. Amphiphil...

  • Article
  • Open Access
3 Citations
2,799 Views
22 Pages

Emergence of Nanoscale Drug Carriers through Supramolecular Self-Assembly of RNA with Calixarene

  • Ruslan Kashapov,
  • Yuliya Razuvayeva,
  • Nadezda Kashapova,
  • Albina Ziganshina,
  • Vadim Salnikov,
  • Anastasiia Sapunova,
  • Alexandra Voloshina and
  • Lucia Zakharova

Supramolecular self-assembly is a powerful tool for the development of polymolecular assemblies that can form the basis of useful nanomaterials. Given the increasing popularity of RNA therapy, the extension of this concept of self-assembly to RNA is...

  • Review
  • Open Access
33 Citations
14,348 Views
20 Pages

Directed Self-Assembly of Block Copolymers for the Fabrication of Functional Devices

  • Christian Pinto-Gómez,
  • Francesc Pérez-Murano,
  • Joan Bausells,
  • Luis Guillermo Villanueva and
  • Marta Fernández-Regúlez

21 October 2020

Directed self-assembly of block copolymers is a bottom-up approach to nanofabrication that has attracted high interest in recent years due to its inherent simplicity, high throughput, low cost and potential for sub-10 nm resolution. In this paper, we...

  • Article
  • Open Access
2 Citations
3,946 Views
12 Pages

Self-Assembly and Gelation Study of Dipeptide Isomers with Norvaline and Phenylalanine

  • Erica Scarel,
  • Giovanni Pierri,
  • Petr Rozhin,
  • Simone Adorinni,
  • Maurizio Polentarutti,
  • Consiglia Tedesco and
  • Silvia Marchesan

2 November 2022

Dipeptides have emerged as attractive building blocks for supramolecular materials thanks to their low-cost, inherent biocompatibility, ease of preparation, and environmental friendliness as they do not persist in the environment. In particular, hydr...

  • Article
  • Open Access
11 Citations
4,433 Views
11 Pages

Directed Self-Assembly of Polystyrene Nanospheres by Direct Laser-Writing Lithography

  • Eleonora Cara,
  • Federico Ferrarese Lupi,
  • Matteo Fretto,
  • Natascia De Leo,
  • Mauro Tortello,
  • Renato Gonnelli,
  • Katia Sparnacci and
  • Luca Boarino

7 February 2020

In this work, we performed a systematic study on the effect of the geometry of pre-patterned templates and spin-coating conditions on the self-assembling process of colloidal nanospheres. To achieve this goal, large-scale templates, with different si...

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