Endothelial Contributions to Zebrafish Heart Regeneration
AbstractStudies over the past two decades have shown heart regeneration in zebrafish to be a dynamic process, choreographed by multiple cell types. In particular, recent work has identified revascularization of the wound to be a sentinel event during heart regeneration. The cardiac endothelium has emerged as a key orchestrator of heart regeneration, influencing cardiomyocyte hyperplasia and tissue morphogenesis. Here, we review how the coronary vasculature regenerates after injury, how signaling pathways link the cardiac endothelium to heart regeneration, and how understanding these signaling dynamics can lead to targeted therapies for heart regeneration. View Full-Text
Share & Cite This Article
Fernandez, C.E.; Bakovic, M.; Karra, R. Endothelial Contributions to Zebrafish Heart Regeneration. J. Cardiovasc. Dev. Dis. 2018, 5, 56.
Fernandez CE, Bakovic M, Karra R. Endothelial Contributions to Zebrafish Heart Regeneration. Journal of Cardiovascular Development and Disease. 2018; 5(4):56.Chicago/Turabian Style
Fernandez, Cristina E.; Bakovic, Melanie; Karra, Ravi. 2018. "Endothelial Contributions to Zebrafish Heart Regeneration." J. Cardiovasc. Dev. Dis. 5, no. 4: 56.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.