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Flavonoids and Other Phenolic Compounds from Medicinal Plants for Pharmaceutical and Medical Aspects: An Overview
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Flavonoids from Nelumbo nucifera Gaertn., a Medicinal Plant: Uses in Traditional Medicine, Phytochemistry and Pharmacological Activities

Department of Pharmaceutical Botany, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand
Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
Laboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC EA1207), INRA USC1328, Plant Lignans Team, Université d’Orléans, Pôle Universitaire d’Eure et Loir, 21 rue de Loigny la Bataille, 28000 Chartres, France
Bioactifs et Cosmétiques, GDR 3711 COSMACTIFS, CNRS/Université d’Orléans, 45067 Orléans CÉDEX 2, France
Author to whom correspondence should be addressed.
Medicines 2018, 5(4), 127;
Received: 31 October 2018 / Revised: 15 November 2018 / Accepted: 20 November 2018 / Published: 23 November 2018
(This article belongs to the Special Issue Antioxidant and Anti-aging Action of Plant Polyphenols)
PDF [2001 KB, uploaded 23 November 2018]


Nelumbo nucifera Gaertn. has been used as an important ingredient for traditional medicines since ancient times, especially in Asian countries. Nowadays, many new or unknown phytochemical compounds from N. nucifera are still being discovered. Most of the current research about pharmacological activity focus on nuciferine, many other alkaloids, phenolic compounds, etc. However, there is no current review emphasizing on flavonoids, which is one of the potent secondary metabolites of this species and its pharmacological activities. Therefore, following a taxonomic description, we aim to illustrate and update the diversity of flavonoid phytochemical compounds from N. nucifera, the comparative analysis of flavonoid compositions and contents in various organs. The uses of this species in traditional medicine and the main pharmacological activities such as antioxidant, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic and anti-cancer activities are also illustrated in this works. View Full-Text
Keywords: Nelumbo nucifera; flavonoids; traditional medicine; pharmacological activities Nelumbo nucifera; flavonoids; traditional medicine; pharmacological activities

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Tungmunnithum, D.; Pinthong, D.; Hano, C. Flavonoids from Nelumbo nucifera Gaertn., a Medicinal Plant: Uses in Traditional Medicine, Phytochemistry and Pharmacological Activities. Medicines 2018, 5, 127.

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