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The Phytochemistry of Cherokee Aromatic Medicinal Plants

Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA
Aromatic Plant Research Center, 230 N 1200 E, Suite 102, Lehi, UT 84043, USA
Medicines 2018, 5(4), 121;
Received: 25 October 2018 / Revised: 6 November 2018 / Accepted: 8 November 2018 / Published: 12 November 2018
(This article belongs to the Special Issue Plant-Derived Medicines and Biological Activity Evaluation)
PDF [1274 KB, uploaded 12 November 2018]


Background: Native Americans have had a rich ethnobotanical heritage for treating diseases, ailments, and injuries. Cherokee traditional medicine has provided numerous aromatic and medicinal plants that not only were used by the Cherokee people, but were also adopted for use by European settlers in North America. Methods: The aim of this review was to examine the Cherokee ethnobotanical literature and the published phytochemical investigations on Cherokee medicinal plants and to correlate phytochemical constituents with traditional uses and biological activities. Results: Several Cherokee medicinal plants are still in use today as herbal medicines, including, for example, yarrow (Achillea millefolium), black cohosh (Cimicifuga racemosa), American ginseng (Panax quinquefolius), and blue skullcap (Scutellaria lateriflora). This review presents a summary of the traditional uses, phytochemical constituents, and biological activities of Cherokee aromatic and medicinal plants. Conclusions: The list is not complete, however, as there is still much work needed in phytochemical investigation and pharmacological evaluation of many traditional herbal medicines. View Full-Text
Keywords: Cherokee; Native American; traditional herbal medicine; chemical constituents; pharmacology Cherokee; Native American; traditional herbal medicine; chemical constituents; pharmacology

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Setzer, W.N. The Phytochemistry of Cherokee Aromatic Medicinal Plants. Medicines 2018, 5, 121.

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