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Review

Recent Insights into Eco-Friendly Extraction Techniques for Obtaining Bioactive Compounds from Fruit Seed Oils

by
Sandra Rodríguez-Blázquez
*,
Esther Gómez-Mejía
,
Noelia Rosales-Conrado
and
María Eugenia León-González
*
Department of Analytical Chemistry, Faculty of Chemistry Sciences, Complutense University of Madrid, 28040 Madrid, Spain
*
Authors to whom correspondence should be addressed.
Foods 2025, 14(13), 2271; https://doi.org/10.3390/foods14132271
Submission received: 30 May 2025 / Revised: 19 June 2025 / Accepted: 24 June 2025 / Published: 26 June 2025

Abstract

The valorization of agri-food waste has emerged as a global priority. In this context, fruit seed waste is being investigated for oil extraction due to its richness in bioactive compounds with remarkable health benefits. This review (2020–2025) focuses on the current state of eco-friendly extraction techniques for obtaining high-yield oils enriched with compounds such as tocopherols, polyphenols, fatty acids, phytosterols, and carotenoids. A comparison of the present method with conventional extraction techniques reveals several notable distinctions. Conventional methods are generally characterized by prolonged extraction times, elevated temperatures, and high amounts of solvents and/or energy. The findings of this review suggest that the extraction methodologies employed exerts a substantial influence on the yield and bioactive composition of the oil, which in turn affects its health-promoting properties. Furthermore, the results have demonstrated that alternative methodologies (microwave-assisted extraction, ultrasound-assisted extraction, pressurized liquid extraction, electric pulse extraction, enzyme-assisted extraction, subcritical extraction, and combinations thereof) have analogous oil yields in comparison with conventional methods. In addition, these oils present a superior bioactive profile with feasible potential in industrial and health applications. The novelty of this work lies in its emphasis on the valorization of fruit seed waste, as well as its sustainable approach. This sustainable approach utilizes experimental design strategies, the implementation of developments that employ comprehensive ecological metrics, and the latest trends in the application of artificial intelligence.
Keywords: agri-food residues; fruit seed oils; bioactive compounds; green extraction techniques; design of experiments; green metrics; artificial intelligence; industrial applications agri-food residues; fruit seed oils; bioactive compounds; green extraction techniques; design of experiments; green metrics; artificial intelligence; industrial applications

Share and Cite

MDPI and ACS Style

Rodríguez-Blázquez, S.; Gómez-Mejía, E.; Rosales-Conrado, N.; León-González, M.E. Recent Insights into Eco-Friendly Extraction Techniques for Obtaining Bioactive Compounds from Fruit Seed Oils. Foods 2025, 14, 2271. https://doi.org/10.3390/foods14132271

AMA Style

Rodríguez-Blázquez S, Gómez-Mejía E, Rosales-Conrado N, León-González ME. Recent Insights into Eco-Friendly Extraction Techniques for Obtaining Bioactive Compounds from Fruit Seed Oils. Foods. 2025; 14(13):2271. https://doi.org/10.3390/foods14132271

Chicago/Turabian Style

Rodríguez-Blázquez, Sandra, Esther Gómez-Mejía, Noelia Rosales-Conrado, and María Eugenia León-González. 2025. "Recent Insights into Eco-Friendly Extraction Techniques for Obtaining Bioactive Compounds from Fruit Seed Oils" Foods 14, no. 13: 2271. https://doi.org/10.3390/foods14132271

APA Style

Rodríguez-Blázquez, S., Gómez-Mejía, E., Rosales-Conrado, N., & León-González, M. E. (2025). Recent Insights into Eco-Friendly Extraction Techniques for Obtaining Bioactive Compounds from Fruit Seed Oils. Foods, 14(13), 2271. https://doi.org/10.3390/foods14132271

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