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Volume 149
Issue 2
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Swiss Archives of Neurology, Psychiatry and Psychotherapy is published by MDPI from Volume 176 Issue 1 (2026). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with the previous journal publisher.

Swiss Arch. Neurol. Psychiatry Psychother., Volume 149, Issue 2 (01 1998) – 6 articles , Pages 59-88

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173 KB  
Article
Lamotrigin bei schwierig zu behandelnden Epilepsien – eine offene Studie an 437 Patienten
by Bernhard J. Steinhoff and S. R. G. Stodieck
Swiss Arch. Neurol. Psychiatry Psychother. 1998, 149(2), 82-88; https://doi.org/10.4414/sanp.1998.01028 - 1 Jan 1998
Viewed by 42
Abstract
This open multicenter study investigated the effects of add-on lamotrigine in 437 patients with intractable epilepsies. Main outcome variable was the tolerability under outpatient treatment conditions. Seizure frequency was the secondary outcome variable. In 70% of all patients at least one adverse event [...] Read more.
This open multicenter study investigated the effects of add-on lamotrigine in 437 patients with intractable epilepsies. Main outcome variable was the tolerability under outpatient treatment conditions. Seizure frequency was the secondary outcome variable. In 70% of all patients at least one adverse event was documented, 29.5% of which were interpreted as being associated with the study drug. None of these were sustained if lamotrigine was reduced or discontinued. Tiredness was the most frequent adverse event with a rate of 15% followed by vertigo, diplopia, nausea, headache, ataxia, vomiting, leukopenia, blurred vision, tremor and exanthema. We suggest that the high incidence of tiredness may have resulted from the frequent combination of lamotrigine and carbamazepine (63%) reflecting a specific interaction. The comparison between the baseline seizure frequency and at the last study visit revealed that 51 patients (12%) became seizure-free and that the seizure frequency was reduced by at least 75% and 50% in additional 50 (11%) and 60 (14%) patients, respectively. Full article
188 KB  
Abstract
First congress held by the Swiss Society of Neurorehabilitation
by Thomas Kay
Swiss Arch. Neurol. Psychiatry Psychother. 1998, 149(2), 79-81; https://doi.org/10.4414/sanp.1998.01029 - 1 Jan 1998
Viewed by 30
Abstract
Minor head injury and whiplash can occur with or without disruption of brain function [...] Full article
141 KB  
Case Report
Neural basis of neuropsychological rehabilitation
by Stephanie Clarke
Swiss Arch. Neurol. Psychiatry Psychother. 1998, 149(2), 73-78; https://doi.org/10.4414/sanp.1998.01027 - 1 Jan 1998
Viewed by 33
Abstract
Neuropsychological rehabilitation is often guided by pragmatic approaches. There is, however, a strong belief that models of recovery derived from cognitive and basic neurosciences may yield more efficient strategies. This paper summarises evidence from neuropsychological, activation and anatomical studies, which supports a model [...] Read more.
Neuropsychological rehabilitation is often guided by pragmatic approaches. There is, however, a strong belief that models of recovery derived from cognitive and basic neurosciences may yield more efficient strategies. This paper summarises evidence from neuropsychological, activation and anatomical studies, which supports a model of parallel distributed processing of human cognitive functions. Parallel distributed processing models can account for recovery after brain damage and may prove useful for designing new rehabilitation strategies in future. Full article
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110 KB  
Case Report
Acute management of mild traumatic brain injury
by François Porchet
Swiss Arch. Neurol. Psychiatry Psychother. 1998, 149(2), 68-72; https://doi.org/10.4414/sanp.1998.01026 - 1 Jan 1998
Cited by 1 | Viewed by 38
Abstract
Mild head injury (MHI) accounts for a substantial proportion of persons admitted to a hospital for brain injury. The management of these patients remains, however, controversial. A modified classification of MHI suggests the segregation of patients with Glasgow Coma Scale scores of 15 [...] Read more.
Mild head injury (MHI) accounts for a substantial proportion of persons admitted to a hospital for brain injury. The management of these patients remains, however, controversial. A modified classification of MHI suggests the segregation of patients with Glasgow Coma Scale scores of 15 from those with scores of 14 or 13 because the latter group is more likely to present intracranial lesions requiring neurosurgical intervention. A computed tomographic (CT) scanning is therefore recommended for all patients with GCS scores of 13 to 14 as a triage device to avoid nondetection of patients with susceptible serious intracranial complications. Patients suffering of a MHI, who have normal results on neurological examination and negative findings on a CT scan, have very small risk of requiring treatment (2%) and no risk of requiring craniotomy. They can be discharged the same day. This management increases the quality of care and decreases the financial expenses. Full article
124 KB  
Case Report
Whiplash injuries
by Randolph W. Evans
Swiss Arch. Neurol. Psychiatry Psychother. 1998, 149(2), 60-67; https://doi.org/10.4414/sanp.1998.01025 - 1 Jan 1998
Viewed by 33
Abstract
Historical note and nomenclature [...] Full article
80 KB  
Editorial
Editorial: Mild traumatic brain injury Leichte traumatische Hirnverletzung
by Th. Ettlin
Swiss Arch. Neurol. Psychiatry Psychother. 1998, 149(2), 59; https://doi.org/10.4414/sanp.1998.01024 - 1 Jan 1998
Viewed by 32
Abstract
Mild traumatic brain injury was the topic of the first congress held by the Swiss Society of Neurorehabilitation at Montreux (June 27 and 28, 1997) [...] Full article
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